Acylated 1H-1,2,4-triazol-5-amines targeting human coagulation factor XIIa and thrombin: Conventional and microscale synthesis, anticoagulant properties, and mechanism of action

Korff M, Imberg L, Will JM, Bückreiß N, Kalinina SA, Wenzel BM, Kastner GA, Daniliuc CG, Barth M, Ovsepyan RA, Butov KR, Humpf HU, Lehr M, Panteleev MA, Poso A, Karst U, Steinmetzer T, Bendas G, Kalinin DV.