Professorship of Pharmaceutical Chemistry (Prof. Lehr)

Status: Organisation is ended

Website: https://www.uni-muenster.de/Chemie.pz/forschen/ag/lehr/

Address:

Corrensstr. 48

48149 Münster

Germany

Publications

Development and validation of a bioanalytical method for the quantification of methotrexate from serum and capillary blood using volumetric absorptive microsampling (VAMS) and on-line solid phase extraction (SPE) LC-MS. Opitz P, Fobker M, Fabian J, Hempel G (2024) In: Journal of Chromatographic Science, 1715, 464610. doi:10.1016/j.chroma.2023.464610 Research article (journal) \| Peer reviewed \| Published
HPLC fluorescence assay for measuring the activity of NAPE-PLD and the action of inhibitors affecting this enzyme. Lange, Thomas; Depmeier, Tim; Strünker, Timo; Lehr, Matthias (2023) In: Journal of Pharmaceutical and Biomedical Analysis, 229. doi:10.1016/j.jpba.2023.115354 Research article (journal) \| Peer reviewed \| Published
Synthesis, activity, metabolic stability and cell permeability of new cytosolic phospholipase A2α inhibitors with 1-indolyl-3-phenoxypropan-2-one structure. Subeska A; Voundi ME; Hanekamp W; Mulac D; Langer K; Lehr M (2023) In: Bioorganic and Medicinal Chemistry Letters, 92, 129374-129374. doi:10.1016/j.bmcl.2023.129374 Research article (journal) \| Peer reviewed \| Published
Synthesis and pharmacokinetic properties of novel cPLA2α inhibitors with 1-(carboxyalkylpyrrolyl)-3-aryloxypropan-2-one structure. Subeska A; Althaus J; Hake T; Hanekamp W; Bettenworth D; Mulac D; Langer K; Lehr M (2023) In: Bioorganic & Medicinal Chemistry, 77, 117110-117110. doi:10.1016/j.bmc.2022.117110 Research article (journal) \| Peer reviewed \| Published
Hexafluoroisopropyl carbamates as selective MAGL and dual MAGL/FAAH inhibitors: Biochemical and physicochemical properties. Barth, M.; Rudolph, S.; Kampschulze, J.; Meyer zu Vilsendorf, I.; Hanekamp, W.; Mulac, D.; Langer, K.; Lehr, M. (2022) In: ChemMedChem, 17, e2021007. doi:10.1002/cmdc.202100757 Research article (journal) \| Peer reviewed \| Published

Show all publications (110)

Projects

RTG 2515: Chemical Biology of Ion Channels (Chembion) Duration: 01/10/2019 - 31/03/2024 \| 1st Funding period Funded by: DFG - Research Training Group Type of project: Main DFG-project hosted at University of Münster
Entwicklung von Hemmstoffen des vaskolären Adhäsionsproteins-1 (VAP-1) als neuartige Antiphlogistika Duration: 01/03/2017 - 29/02/2020 Funded by: DFG - Individual Grants Programme Type of project: Individual project
Entwicklung von Hemmstoffen von Phosphatidylinositol-spezifischen Phospholipasen C als biochemische Tools und potentielle neuartige Arzneistoffe Duration: 15/05/2008 - 31/05/2011 Funded by: DFG - Individual Grants Programme Type of project: Individual project

Promotionen

Untersuchungen zur Formulierung flüssiger Arzneistoffe in festen Arzneiformen Candidate: Hortmann, Pascal \| Supervisors: Langer, Prof. Dr. Klaus \| Reviewers: Langer, K.; Lehr, M. Period of time: 01/04/2017 - 19/01/2024 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
HSA-stabilisierte Nanopartikel für intravenöse Anwendungen. Candidate: Adick, Annika \| Supervisors: Langer, Prof. Dr. Klaus \| Reviewers: Lehr, M. Period of time: 01/06/2020 - 31/12/2023 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Synthese und biologische Evaluation von Formyl-Peptid-Rezeptor-1-Liganden für die Analyse der Bindetasche und die Fluoreszenzmarkierung Candidate: Olejua Torres, Karen Elisabeth \| Supervisors: Wünsch, Bernhard \| Reviewers: Wünsch, Bernhard; Lehr, Matthias Period of time: 01/01/2018 - 28/10/2021 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Stereoselective Synthesis and Pharmacological Evaluation of 2,4-Bridged Piperidine Derivatives Designed to Activate the -Opioid Receptor Candidate: Hendrik Jonas \| Supervisors: Wünsch, Bernhard \| Reviewers: Wünsch, Bernhard; Lehr, Matthias Period of time: 01/11/2017 - 29/09/2021 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Concept of Conformational Restriction: Diastereoselective Synthesis and Pharmacological Evaluation of Ethylenediamine-Based -Opioid Receptor Agonists with… Candidate: Denise Ilari \| Supervisors: Wünsch, Bernhard \| Reviewers: Wünsch, Bernhard; Lehr, Matthias Period of time: 01/11/2017 - 10/06/2021 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

Show all doctorates (37)

Parent organisational units

University of Münster
- Schools and Faculties
  - FB12 - Faculty of Chemistry and Pharmacy
    - Institute for Pharmaceutical and Medical Chemistry