Radiation synergizes with antitumor activity of CD13-targeted tissue factor in a HT1080 xenograft model of human soft tissue sarcoma
Brand V, Greve B, Bölling T, Eich HT, Willich N, Harrach S, Hintelmann H, Lenz G, Mesters RM, Kessler T, Schliemann C, Berdel WE, Schwöppe C
Research article (journal) | Peer reviewedAbstract
Irradiation renders tumor and tumor vascular cells procoagulant by PS upregulation on their outer surface and radiotherapy can significantly improve the therapeutic antitumor efficacy of tTF-NGR in the xenograft model used. This synergistic effect will influence design of future clinical combination studies.
Details about the publication
Journal: PloS one (PLoS One)
Volume: 15(2)
Status: Published
Release year: 2020 (21/02/2020)
Language in which the publication is written: English
Authors from the University of Münster
| Berdel, Wolfgang Eduard | Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A) |
| Bölling, Tobias | Clinic for Radiotherapy |
| Eich, Hans Theodor | Clinic for Radiotherapy |
| Greve, Burkhard | Clinic for Radiotherapy |
| Harrach, Saliha | Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A) |
| Keßler, Torsten | Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A) |
| Lenz, Georg | Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A) |
| Mesters, Rolf Michael | Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A) |
| Schliemann, Christoph | Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A) |
| Schwöppe, Christian | Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A) |
| Willich, Normann | Clinic for Radiotherapy |
| Zerbst, Caroline | Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A) |