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Prof. Dr. Wolfgang Eduard Berdel

Current affiliations

Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A)

Curriculum Vitae (CV)

Molecular leukemogenesis and oncogenesis
Tumor angiogenesis and vascular targeting
Lung cancer metastasis

Academic Education
10/1978 - 04/1979	MD Thesis/Postdoc (Dr. med.), Max Planck Institute of Immunobiology, Freiburg
04/1972 - 10/1978	University of Hamburg, Munich University of Technology, University of Freiburg
Work Experience
since 10/1997	Director, Department of Haematology and Oncology, University Hospital Münster (UKM)
since 10/1997	Full Professor of Medicine (C4), Medical Faculty, University of Münster (WWU)
07/1990 - 09/1997	Associate Professor (C3), Department of Haematology and Oncology, Hospital Benjamin Franklin, Free University of Berlin
07/1988 - 07/1990	Attending Physician, Department of Medicine I, Munich University of Technology
04/1987 - 07/1988	Visiting Associate Professor, Department of Haematology, Emory University, Atlanta, GA, USA
04/1979 - 04/1987	Internship and Fellowship, Department of Medicine I, Munich University of Technology
Functions and Memberships
	American Society of Clinical Oncology (ASCO)
	American Society of Hematology (ASH)
	American Association for Cancer Research (AACR)

Publications

Clonal hematopoiesis in AML long-term survivors: Risk factors and clinical consequences Krauss, Simon M.; Telzerow, Eva; Richter, Daniel; Moret, Anna S.; Rothenberg-Thurley, Maja; Sauerland, Cristina; Weigert, Anne; Fraccaroli, Alessia; Tischer, Johanna; Ziemann, Frank; Goetze, Katharina S.; Berdel, Wolfgang E.; Woermann, Bernhard; Krug, Utz; Braess, Jan; Heussner, Pia; Enard, Wolfgang; Hiddemann, Wolfgang; Spiekermann, Karsten; Goerlich, Dennis; Platzbecker, Uwe; Metzeler, Klaus H. (2025) In: HemaSphere, 9(7). doi:10.1002/hem3.70183 Research article (journal) \| Peer reviewed \| Published
Quality of life and life satisfaction in long-term survivors of acute myeloid leukemia Telzerow, Eva; Goerlich, Dennis; Sauerland, Cristina; Rothenberg-Thurley, Maja; Moret, Anna Sophia; Krauss, Simon M.; Mumm, Friederike H. A.; Amler, Susanne; Berdel, Wolfgang E.; Woermann, Bernhard J.; Krug, Utz; Braess, Jan; Heussner, Pia; Hiddemann, Wolfgang; Spiekermann, Karsten; Metzeler, Klaus H. (2025) In: Leukemia, online. doi:10.1038/s41375-025-02735-y Research article (journal) \| Peer reviewed \| Published
Deep learning predicts therapy-relevant genetics in acute myeloid leukemia from Pappenheim-stained bone marrow smears Kockwelp, Jacqueline; Thiele, Sebastian; Bartsch, Jannis; Haalck, Lars; Gromoll, Jörg; Schlatt, Stefan; Exeler, Rita; Bleckmann, Annalen; Lenz, Georg; Wolf, Sebastian; Steffen, Björn; Berdel, Wolfgang Eduard; Schliemann, Christoph; Risse, Benjamin; Angenendt, Linus (2024) In: Blood Advances, 8(1), 70-79. doi:10.1182/bloodadvances.2023011076 Research article (journal) \| Peer reviewed \| Published
Improving risk stratification for 2022 European LeukemiaNet favorable- risk patients with acute myeloid leukemia Archer, Kellie J.; Fu, Han; Mrozek, Krzysztof; Nicolet, Deedra; Mims, Alice S.; Uy, Geoffrey L.; Stock, Wendy; Byrd, John C.; Hiddemann, Wolfgang; Metzeler, Klaus H.; Rausch, Christian; Krug, Utz; Sauerland, Cristina; Goerlich, Dennis; Berdel, Wolfgang E.; Woermann, Bernhard J.; Braess, Jan; Spiekermann, Karsten; Herold, Tobias; Eisfeld, Ann-Kathrin (2024) In: The Innovation, 5(6). doi:10.1016/j.xinn.2024.100719 Research article (journal) \| Peer reviewed \| Published
A randomized phase 2 trial of nintedanib and low-dose cytarabine in elderly patients with acute myeloid leukemia ineligible for intensive chemotherapy Berdel AF, Koch R, Gerss J, Hentrich M, Peceny R, Bartscht T, Steffen B, Bischoff M, Spiekermann K, Angenendt L, Mikesch JH, Kewitz T, Butterfass-Bahloul T, Serve H, Lenz G, Berdel WE, Krug U, Schliemann C (2023) In: Annals of Hematology, 102, 63-72. doi:10.1007/s00277-022-05025-0 Research article (journal) \| Peer reviewed \| Published

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Projects

EXC 1003 FF-2014-03 – In vivo intratumoral accumulation of cytotoxic drugs by tumor vascular infarction with retargeted tissue factor tTF-NGR Duration: 01/04/2014 - 31/03/2015 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
Antivaskuläre Therapiestrategien durch gezielte Gewebefaktor-induzierte Blutgerinnung in malignen Tumoren Duration: 01/02/2014 - 31/01/2016 Funded by: Deutsche Krebshilfe e.V. Type of project: Individual project
EXC 1003 C2 - Monitoring and Targeting of Tumour-Associated Vessels and Cells Duration: 01/11/2012 - 31/10/2019 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
Antivaskuläre Therapiestrategien durch gezielte Gewebefaktor-induzierte Blutgerinnung in malignen Tumoren Duration: 01/01/2010 - 31/12/2013 Funded by: Deutsche Krebshilfe e.V. Type of project: Individual project
A Randomized, Risk and Age Adapted Comparison of the Dose-Dense Regimen S-HAM (sequential high dose cytosine arabinoside and mitoxantrone) versus Standard… (AMLCG 2008) Duration: 01/04/2009 - 31/03/2018 Funded by: Deutsche Krebshilfe e.V. Type of project: Individual project

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Prizes

Aufnahme in die Focus Ärzteliste 2017 Awarded by: Focus Award given to: Brehler, Randolf; Kliesch, Sabine; Zitzmann, Michael; Arolt, Volker; Senninger, Norbert; Brand, Eva; Pavenstädt, Hermann-Joseph; Heuft, Gereon; Bürklein, Sebastian; Schäfer, Edgar; Kurlemann, Gerhard; Ochman, Sabine; Langer, Martin; Malec, Edward; Martens, Sven; Hohoff, Ariane; Berdel, Wolfgang; Wiendl, Heinz; Eter, Nicole; Luger, Thomas; Warnecke, Tobias; Ehmke, Benjamin; Klockenbusch, Walter; Liem, Dennis; Herbort, Mirco; Eich, Theodor; Raschke, Michael; Semjonow, Axel; Schrader, Jan Announced at: 15/06/2017 \| Date of awarding: 15/06/2017 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Ärzteliste 2016 Awarded by: Focus Award given to: Brehler, Randolf; Kliesch, Sabine; Zitzmann, Michael; Arolt, Volker; Senninger, Norbert; Brand, Eva; Pävenstädt Hermann; Heuft, Gereon; Bürklein, Sebastian; Schäfer, Edger; Kurlemann, Gerhard; Ochman, Sabine; Torsello, Giovanni; Langer,Martin; Sunderkötter, Cord; Malec, Edward; Martens,Sven;Hohoff,Ariane; Berdel, Wolfgang; Eter, Nicole; Brehler,Randolf; Luger, Thomas; Warnecke, Tobias; Ehmke, Benjamin; Klockenbusch, Walter; Gralow, Ingrid; Liem, Dennis; Eich, Theodor; Senninger, Norbert; Raschke, Michael Announced at: 15/07/2016 \| Date of awarding: 15/07/2016 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Ärzteliste 2015 Awarded by: Focus Award given to: Arolt, Volker; Wiendl, Heinz; Rijcken, Emile; Martens, Sven; Semjonow, Axel; Klockenbusch, Walter; Eich, Hans-Theodor; Liem, Dennis;Brehler, Randolf; Senninger, Norbert; Brand, Eva; Pavenstädt, Hermann-Joseph; Heuft, Gereon; Kurlemann, Gerhard; Bürklein, Sebastian; Schäfer, Edgar; Torsello, Giovanni; Langer, Martin; Malec, Edward; Hohoff, Ariane; Berdel, Wolfgang; Eter, Nicole; Luger, Thomas; Warnecke, Tobias; Ehmke, Benjamin; Gralow, Ingrid; Raschke, Michael; Announced at: 01/01/2015 \| Date of awarding: 01/01/2015 Type of distinction: Research award or other distinction
PHOENIX Pharmazie Wissenschaftspreis 2014 Awarded by: PHOENIX group Award given to: Berdel, Wolfgang; Schliemann, Christoph Date of awarding: 15/11/2014 Type of distinction: Best publication award
Aufnahme in die Focus-Ärzteliste 2014 Awarded by: Focus Award given to: Colombo-Benkmann; Brehler; Arolt; Senninger; Brand; Pavenstädt; Heuft; Bürklein; Schäfer; Torsello; Langer; Malex; Martens; Hohoff; Berdel; Eter; Luger; Ehmke; Klockenbusch; Gralow; Liem; Eich; Semjonow Announced at: 15/07/2014 \| Date of awarding: 15/07/2014 Type of distinction: Research award or other distinction

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Doctorates

Untersuchung des Einflusses von Hypoxie auf die differentielle Genexpression in parentalen und in vivo selektionierten humanen Lungenadenokarzinomzelllinien Candidate: Jungen, Dominik \| Supervisors: Berdel, Wolfgang; Klämbt, Christian; Barnekow, Angelika Period of time: 28/08/2005 - 12/04/2010 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Mutationsanalyse der Tyrosinkinasedomäne des EGFR-Gens bei Patienten mit Pankreaskarzinom Candidate: Oertel, Anne Friederike \| Supervisors: Berdel, Wolfgang Period of time: until 24/11/2008 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Deskriptive Untersuchungen zur Erythropoese bei schwerer Malaria-Anämie Candidate: Appelmann, Iris \| Supervisors: Berdel, Wolfgang Period of time: until 27/10/2008 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Untersuchungen zur Modulation der intrazellularen Aktivierung von Cytarabin durch Fludarabin und Hydroxyurea an kultivierten Leukämiezellen Candidate: Schrief, Gerlinde \| Supervisors: Boos, Joachim; Berdel, Wolfgang Period of time: until 31/12/2000 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Allergische Nebenwirkungen unter L-Asparaginasetherapie im Studienprotokoll ALL BFM 90 und einer pilotisierten Behandlungsphase zum Studienprotokoll ALL BFM 95 Candidate: Ehle, Christian \| Supervisors: Boos, Joachim; Berdel, Wolfgang Period of time: until 12/04/2000 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster