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Prof. Dr. Wolfgang Eduard Berdel

Current affiliations

Medical Clinic of Internal Medicine A (Hematology, Oncology, and Oneumology) (Med A)

Curriculum Vitae (CV)

Molecular leukemogenesis and oncogenesis
Tumor angiogenesis and vascular targeting
Lung cancer metastasis

Academic Education
10/1978 - 04/1979	MD Thesis/Postdoc (Dr. med.), Max Planck Institute of Immunobiology, Freiburg
04/1972 - 10/1978	University of Hamburg, Munich University of Technology, University of Freiburg
Work Experience
since 10/1997	Director, Department of Haematology and Oncology, University Hospital Münster (UKM)
since 10/1997	Full Professor of Medicine (C4), Medical Faculty, University of Münster (WWU)
07/1990 - 09/1997	Associate Professor (C3), Department of Haematology and Oncology, Hospital Benjamin Franklin, Free University of Berlin
07/1988 - 07/1990	Attending Physician, Department of Medicine I, Munich University of Technology
04/1987 - 07/1988	Visiting Associate Professor, Department of Haematology, Emory University, Atlanta, GA, USA
04/1979 - 04/1987	Internship and Fellowship, Department of Medicine I, Munich University of Technology
Functions and Memberships
	American Society of Clinical Oncology (ASCO)
	American Society of Hematology (ASH)
	American Association for Cancer Research (AACR)

Publications

Deep learning predicts therapy-relevant genetics in acute myeloid leukemia from Pappenheim-stained bone marrow smears Kockwelp, Jacqueline; Thiele, Sebastian; Bartsch, Jannis; Haalck, Lars; Gromoll, Jörg; Schlatt, Stefan; Exeler, Rita; Bleckmann, Annalen; Lenz, Georg; Wolf, Sebastian; Steffen, Björn; Berdel, Wolfgang Eduard; Schliemann, Christoph; Risse, Benjamin; Angenendt, Linus (2024) In: Blood Advances, 8(1) Type of Publication: Research article (journal)
A randomized phase 2 trial of nintedanib and low-dose cytarabine in elderly patients with acute myeloid leukemia ineligible for intensive chemotherapy Berdel AF, Koch R, Gerss J, Hentrich M, Peceny R, Bartscht T, Steffen B, Bischoff M, Spiekermann K, Angenendt L, Mikesch JH, Kewitz T, Butterfass-Bahloul T, Serve H, Lenz G, Berdel WE, Krug U, Schliemann C (2023) In: Annals of Hematology, 102 Type of Publication: Research article (journal)
Different treatment strategies versus a common standard arm (CSA) in patients with newly diagnosed AML over the age of 60 years: a randomized German inter-group study Niederwieser D, Lang T, Krahl R, Heinicke T, Maschmeyer G, Al-Ali HK, Schwind S, Jentzsch M, Cross M, Kahl C, Wolf HH, Sayer H, Schulze A, Dreger P, Hegenbart U, Krämer A, Junghanss C, Mügge LO, Hähling D, Hirt C, Späth C, Peter N, Opitz B, Florschütz A, Reifenrath K, Zojer N, Scholl S, Pönisch W, Heyn S, Vucinic V, Hochhaus A, Aul C, Giagounidis A, Balleisen L, Oldenkott B, Staib P, Kiehl M, Schütte W, Naumann R, Eimermacher H, Dörken B, Sauerland C, Lengfelder E, Hiddemann W, Wörmann B, Müller-Tidow C, Serve H, Schliemann C, Hehlmann R, Berdel WE, Pfirrmann M, Krug U, Hoffmann VS (2023) In: Annals of Hematology, 102(3) Type of Publication: Research article (journal)
Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML. Batcha AMN, Buckup N, Bamopoulos SA, Jurinovic V, Rothenberg-Thurley M, Gittinger H, Ksienzyk B, Dufour A, Schneider S, Kontro M, Saad J, Heckman CA, Sauerland CM, Görlich D, Berdel WE, Wörmann B, Krug U, Braess J, Mansmann UR, Hiddemann W, Spiekermann K, Metzeler KH, Herold T (2023) In: Blood Advances, 7(6) Type of Publication: Research article (journal)
Low-density lipoprotein receptor (LDLR) is an independent adverse prognostic factor in acute myeloid leukaemia Floeth M; Elges S; Gerss J; Schwöppe C; Kessler T; Herold T; Wardelmann E; Berdel WE; Lenz G; Mikesch JH; Hartmann W; Schliemann ;, Angenendt L (2021) In: British Journal of Haematology, 192(3) Type of Publication: Research article (journal)

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Projects

EXC 1003 FF-2014-03 – In vivo intratumoral accumulation of cytotoxic drugs by tumor vascular infarction with retargeted tissue factor tTF-NGR Duration: 01/04/2014 - 31/03/2015 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
EXC 1003 C2 - Monitoring and Targeting of Tumour-Associated Vessels and Cells Duration: 01/11/2012 - 31/10/2019 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
A Randomized, Risk and Age Adapted Comparison of the Dose-Dense Regimen S-HAM (sequential high dose cytosine arabinoside and mitoxantrone) versus Standard… (AMLCG 2008) Duration: 01/04/2009 - 31/03/2018 Funded by: Deutsche Krebshilfe e.V. Type of project: Individual project
Strengthen and develop scientific and technological excellence in research and therapy of leukemia (CML, AML, ALL, CLL, MDS, CMPD) by integration of the… (EUROPEAN LEUKEMIANET) Duration: 01/01/2004 - 28/02/2011 Funded by: EC FP 6 - Networks of Excellence Type of project: EU-project hosted outside University of Münster

Prizes

Aufnahme in die Focus Ärzteliste 2017 Awarded by: Focus Award given to: Brehler, Randolf; Kliesch, Sabine; Zitzmann, Michael; Arolt, Volker; Senninger, Norbert; Brand, Eva; Pavenstädt, Hermann-Joseph; Heuft, Gereon; Bürklein, Sebastian; Schäfer, Edgar; Kurlemann, Gerhard; Ochman, Sabine; Langer, Martin; Malec, Edward; Martens, Sven; Hohoff, Ariane; Berdel, Wolfgang; Wiendl, Heinz; Eter, Nicole; Luger, Thomas; Warnecke, Tobias; Ehmke, Benjamin; Klockenbusch, Walter; Liem, Dennis; Herbort, Mirco; Eich, Theodor; Raschke, Michael; Semjonow, Axel; Schrader, Jan Announced at: 15/06/2017 \| Date of awarding: 15/06/2017 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Ärzteliste 2016 Awarded by: Focus Award given to: Brehler, Randolf; Kliesch, Sabine; Zitzmann, Michael; Arolt, Volker; Senninger, Norbert; Brand, Eva; Pävenstädt Hermann; Heuft, Gereon; Bürklein, Sebastian; Schäfer, Edger; Kurlemann, Gerhard; Ochman, Sabine; Torsello, Giovanni; Langer,Martin; Sunderkötter, Cord; Malec, Edward; Martens,Sven;Hohoff,Ariane; Berdel, Wolfgang; Eter, Nicole; Brehler,Randolf; Luger, Thomas; Warnecke, Tobias; Ehmke, Benjamin; Klockenbusch, Walter; Gralow, Ingrid; Liem, Dennis; Eich, Theodor; Senninger, Norbert; Raschke, Michael Announced at: 15/07/2016 \| Date of awarding: 15/07/2016 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Ärzteliste 2015 Awarded by: Focus Award given to: Arolt, Volker; Wiendl, Heinz; Rijcken, Emile; Martens, Sven; Semjonow, Axel; Klockenbusch, Walter; Eich, Hans-Theodor; Liem, Dennis;Brehler, Randolf; Senninger, Norbert; Brand, Eva; Pavenstädt, Hermann-Joseph; Heuft, Gereon; Kurlemann, Gerhard; Bürklein, Sebastian; Schäfer, Edgar; Torsello, Giovanni; Langer, Martin; Malec, Edward; Hohoff, Ariane; Berdel, Wolfgang; Eter, Nicole; Luger, Thomas; Warnecke, Tobias; Ehmke, Benjamin; Gralow, Ingrid; Raschke, Michael; Announced at: 01/01/2015 \| Date of awarding: 01/01/2015 Type of distinction: Research award or other distinction
PHOENIX Pharmazie Wissenschaftspreis 2014 Awarded by: PHOENIX group Award given to: Berdel, Wolfgang; Schliemann, Christoph Date of awarding: 15/11/2014 Type of distinction: Best publication award
Aufnahme in die Focus-Ärzteliste 2014 Awarded by: Focus Award given to: Colombo-Benkmann; Brehler; Arolt; Senninger; Brand; Pavenstädt; Heuft; Bürklein; Schäfer; Torsello; Langer; Malex; Martens; Hohoff; Berdel; Eter; Luger; Ehmke; Klockenbusch; Gralow; Liem; Eich; Semjonow Announced at: 15/07/2014 \| Date of awarding: 15/07/2014 Type of distinction: Research award or other distinction

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Doctorates

Untersuchung des Einflusses von Hypoxie auf die differentielle Genexpression in parentalen und in vivo selektionierten humanen Lungenadenokarzinomzelllinien Candidate: Jungen, Dominik \| Supervisors: Berdel, Wolfgang; Klämbt, Christian; Barnekow, Angelika Period of time: 28/08/2005 - 12/04/2010 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Mutationsanalyse der Tyrosinkinasedomäne des EGFR-Gens bei Patienten mit Pankreaskarzinom Candidate: Oertel, Anne Friederike \| Supervisors: Berdel, Wolfgang Period of time: until 24/11/2008 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Deskriptive Untersuchungen zur Erythropoese bei schwerer Malaria-Anämie Candidate: Appelmann, Iris \| Supervisors: Berdel, Wolfgang Period of time: until 27/10/2008 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Untersuchungen zur Modulation der intrazellularen Aktivierung von Cytarabin durch Fludarabin und Hydroxyurea an kultivierten Leukämiezellen Candidate: Schrief, Gerlinde \| Supervisors: Boos, Joachim; Berdel, Wolfgang Period of time: until 31/12/2000 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Allergische Nebenwirkungen unter L-Asparaginasetherapie im Studienprotokoll ALL BFM 90 und einer pilotisierten Behandlungsphase zum Studienprotokoll ALL BFM 95 Candidate: Ehle, Christian \| Supervisors: Boos, Joachim; Berdel, Wolfgang Period of time: until 12/04/2000 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster