CRC 656 B01 - Selective Synthesis of Fluorinated Ligands and its 18F-Radiolabelling for PET (SFB 656 B01)
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/06/2005 - 30/06/2017 | 3rd Funding period
Description
This project is focused on the development of new regio- and stereoselective fluorination methodology with high potential for application in radiotracer synthesis. For highly affine new fluorinated caspase inhibitors prepared within this project as well as for those to be explored new radiosyntheses will be developed. In particular, the mechanistic details of a new oxidative desulfurisation-difluorination method will be investigated in order to develop a new way for the preparation of [18F]labeled ligands. Furthermore, new building blocks for the synthesis of fluorinated potential caspase and MMP inhibitors will be explored.
Keywords: 18F Radiotracer
Website of the project: http://www.uni-muenster.de/Sfbmobil/projekte/methoden/b1.html
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Haufe, Günter | Professur für Organische Chemie (Prof. Haufe) |
| Hugenberg, Verena | European Institute of Molecular Imaging (EIMI) |
| Wagner, Stefan | Clinic for Nuclear Medicine |
Applicants from the University of Münster
| Haufe, Günter | Professur für Organische Chemie (Prof. Haufe) |