Professor Dr. Günter Haufe

No current affiliations available for this person. The person is no longer active at the university.

Curriculum Vitae (CV)

Organic fluorine chemistry, fluorination methods including radiofluorination, stereoselective synthesis of fluorinated analogs of natural products and biologically active compounds (enzyme inhibitors)
application of enzymes in organic synthesis, including microbial transformations (‘Biooxygenation’)
alicyclic chemistry including terpenes; total synthesis of natural products

Academic Education
07/1985	Habilitation, University of Leipzig
10/1975	PhD (Dr. rer. nat.), University of Leipzig
03/1972	University Degree in Chemistry, University of Leipzig
Work Experience
since 1991	Professor of Organic Chemistry (C3), Faculty of Chemistry and Pharmacy, University of Münster (WWU)
02/1988 - 1991	Lecturer of Bioorganic Chemistry, University of Leipzig
Functions and Memberships
since 2009	Chair of the Group of Fluorine Chemists within the German Chemical Society
since 2008	Regional Editor (Europe, Africa, Australia) of the Journal of ‘Fluorine Chemistry’
since 2007	Member of the Board, European Institute of Molecular Imaging (EIMI)
since 2005	Vice Chair of the Collaborative Research Centre ‘Molecular Cardiovascular Imaging - From Mice to Man’ – SFB 656
since 1997	Member of the American Chemical Society
since 1973	Member of the German Chemical Society (GDCh)
2008	Co-Editor, ‘Fluorine and Health. Molecular Imaging, Biomedical Materials and Pharmaceuticals’, Elsevier, Amsterdam, together with A. Tressaud
2005 - 2007	Associate Editor, ‘Advances in Fluorine Science’
2004 - 2007	Member of the Editorial Board, ‘Journal of Fluorine Chemistry’
2003	Visiting Professor at the University of Poznan, Poland
2002	Paul Tarrant Visiting Professor at the University of Florida, Gainesville, USA
1995 - 2002	Chair of the Graduate College ‘Highly Reactive Multiple Bond Systems’
1994	Visiting Professor at the University of Lyon, France
Appointments
1999	Offer to a Professorship, Kiel University

Publications

Radical Reactions of Alkyl 2-Bromo-2,2-difluoroacetates with Vinyl Ethers: “Omitted” Examples and Application for the Synthesis of 3,3-Difluoro-GABA Kondratov IS, Bugera MY, Tolmachova NA, Posternak GG, Daniliuk CG, Haufe G (2015) In: Journal of Organic Chemistry, 80, 12258-12264. doi:10.1021/acs.joc.5b02171 Research article (journal) \| Peer reviewed \| Published
New Fluorinated Agonists for Targeting the Sphingosin-1-Phosphate Receptor 1 (S1P1) Shaikh RS, Keul P, Schäfers M, Levkau B, Haufe G (2015) In: ((Bitte Journal prüfen)), 25, 5048-5051. doi:10.1016/jmcl.2015.10.026 Research article (journal) \| Peer reviewed \| Published
Synthesis and Physical-chemical Properties of 3-Fluorocyclobutyl Amines Chernykh AX, Radchenko DX, Kondratov IS, Tolmachova NA, Datsenko OX, Kurkunov MA, Zozulya SX, Kheylik YX, Bartels K, Daniliuk CG, Haufe G (2015) In: European Journal of Organic Chemistry, 2015, 6466-6471. doi:10.1002/ejoc.201500746 Research article (journal) \| Peer reviewed \| Published
Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis Waldmann CM, Hermann S, Faust A, Riemann R, Schober O, Schäfers M, Haufe G, Kopka K (2015) In: ((Bitte Journal prüfen)), 23, 5734-5739. doi:10.1016/j.bmc.2015.07.014 Research article (journal) \| Peer reviewed \| Published
Synthesis of new fluorinated analogs of GABA, Pregabalin bioisosteres, and their effects on [H-3]GABA uptake by rat brain nerve terminals Borisova T, Pozdnyakova N, Shaitanova E, Gerus I, Dudarenko M, Mironets R, Haufe G, Kukhar V (2015) In: ((Bitte Journal prüfen)), 23, 3416-3423. doi:10.1016/j.bmc.2015.06.038 Research article (journal) \| Peer reviewed \| Published

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Projects

New synthetic pathways to polyfluoroalkyl containing amino- and hydroxy acids with potential biological activity Duration: 01/07/2016 - 30/06/2017 \| 2nd Funding period Funded by: DFG - Individual Grants Programme Type of project: Individual project
EXC 1003 FF-2015-03 – CCR6 as a marker of CD4+Th17+ T cells in inflammation: development of specific imaging and therapeutic tools Duration: 01/07/2015 - 30/06/2016 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
EXC 1003 FF-2013-28 - Development of novel, dual purpose, MOBSAM-based, specific inhibitors for MMP-2/9 to image and investigate their activity in inflammatory… Duration: 01/07/2013 - 30/06/2015 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
EXC 1003 A5 - Surface-Targeted Tracking of Individual Cells In Vivo Duration: 01/11/2012 - 31/10/2019 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
Synthesis of new bromodifluoromethyl- and arylthiodifluoromethyl styrenes and alkynes and their application Duration: 13/07/2010 - 31/07/2013 Funded by: DFG - Individual Grants Programme Type of project: Individual project

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Prizes

Election as Member of the European Academy of Sciences (EURASC) Awarded by: European Academy of Sciences (EURASC) Award given to: Haufe, Günter Announced at: 30/11/2015 \| Date of awarding: 15/11/2015 Type of distinction: Research award or other distinction
Friedrich-Wöhler-Prize Awarded by: Chemical Society of German Democratic Republic (GDR) Award given to: Haufe, Günter Date of awarding: 01/01/1985 Type of distinction: Research award or other distinction

Doctorates

Synthesis, optimization and evaluation of bordipyrromethene-fluorophores for the preparation of ligands for multimodal imaging Candidate: Christian Paul Ortmeyer \| Supervisors: Haufe, Günter; Schäfers, Michael; Karst, Uwe Period of time: 01/10/2013 - 02/02/2017 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
3-Pentafluorsulfanyl-prop-1-enal Ein fluorierter Building Block für die organische Synthese Candidate: Husstedt, Wibke Svenja \| Supervisors: Haufe, Günter Period of time: until 11/04/2011 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Fluorinated α-Amino Acids and their Peptides: Synthesis, Biological and Conformational Analysis Candidate: Purkayastha, Nirupam \| Supervisors: Haufe, Günter Period of time: until 05/02/2010 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Metathese von Vinylfluoriden: Ein vielseitiges Werkzeug zur Darstellung monofluorierter Heterocyclen und Alkaloidgerüste Candidate: Stillig, Christian \| Supervisors: Haufe, Günter Period of time: until 22/01/2010 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Neue fluorierte Aminosäurederivate und Aminohydroxamsäurederivate als Matrix-Metalloproteinase Inhibitoren Candidate: Behrends, Malte \| Supervisors: Haufe, Günter Period of time: until 12/10/2009 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

Show all doctorates

Radical Reactions of Alkyl 2-Bromo-2,2-difluoroacetates with Vinyl Ethers: “Omitted” Examples and Application for the Synthesis of 3,3-Difluoro-GABA Kondratov IS, Bugera MY, Tolmachova NA, Posternak GG, Daniliuk CG, Haufe G (2015) In: Journal of Organic Chemistry, 80, 12258-12264. doi:10.1021/acs.joc.5b02171 Research article (journal) \| Peer reviewed \| Published
New Fluorinated Agonists for Targeting the Sphingosin-1-Phosphate Receptor 1 (S1P1) Shaikh RS, Keul P, Schäfers M, Levkau B, Haufe G (2015) In: ((Bitte Journal prüfen)), 25, 5048-5051. doi:10.1016/jmcl.2015.10.026 Research article (journal) \| Peer reviewed \| Published
Synthesis and Physical-chemical Properties of 3-Fluorocyclobutyl Amines Chernykh AX, Radchenko DX, Kondratov IS, Tolmachova NA, Datsenko OX, Kurkunov MA, Zozulya SX, Kheylik YX, Bartels K, Daniliuk CG, Haufe G (2015) In: European Journal of Organic Chemistry, 2015, 6466-6471. doi:10.1002/ejoc.201500746 Research article (journal) \| Peer reviewed \| Published
Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis Waldmann CM, Hermann S, Faust A, Riemann R, Schober O, Schäfers M, Haufe G, Kopka K (2015) In: ((Bitte Journal prüfen)), 23, 5734-5739. doi:10.1016/j.bmc.2015.07.014 Research article (journal) \| Peer reviewed \| Published
Synthesis of new fluorinated analogs of GABA, Pregabalin bioisosteres, and their effects on [H-3]GABA uptake by rat brain nerve terminals Borisova T, Pozdnyakova N, Shaitanova E, Gerus I, Dudarenko M, Mironets R, Haufe G, Kukhar V (2015) In: ((Bitte Journal prüfen)), 23, 3416-3423. doi:10.1016/j.bmc.2015.06.038 Research article (journal) \| Peer reviewed \| Published

New synthetic pathways to polyfluoroalkyl containing amino- and hydroxy acids with potential biological activity Duration: 01/07/2016 - 30/06/2017 \| 2nd Funding period Funded by: DFG - Individual Grants Programme Type of project: Individual project
EXC 1003 FF-2015-03 – CCR6 as a marker of CD4+Th17+ T cells in inflammation: development of specific imaging and therapeutic tools Duration: 01/07/2015 - 30/06/2016 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
EXC 1003 FF-2013-28 - Development of novel, dual purpose, MOBSAM-based, specific inhibitors for MMP-2/9 to image and investigate their activity in inflammatory… Duration: 01/07/2013 - 30/06/2015 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
EXC 1003 A5 - Surface-Targeted Tracking of Individual Cells In Vivo Duration: 01/11/2012 - 31/10/2019 \| 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster
Synthesis of new bromodifluoromethyl- and arylthiodifluoromethyl styrenes and alkynes and their application Duration: 13/07/2010 - 31/07/2013 Funded by: DFG - Individual Grants Programme Type of project: Individual project

Synthesis, optimization and evaluation of bordipyrromethene-fluorophores for the preparation of ligands for multimodal imaging Candidate: Christian Paul Ortmeyer \| Supervisors: Haufe, Günter; Schäfers, Michael; Karst, Uwe Period of time: 01/10/2013 - 02/02/2017 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
3-Pentafluorsulfanyl-prop-1-enal Ein fluorierter Building Block für die organische Synthese Candidate: Husstedt, Wibke Svenja \| Supervisors: Haufe, Günter Period of time: until 11/04/2011 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Fluorinated α-Amino Acids and their Peptides: Synthesis, Biological and Conformational Analysis Candidate: Purkayastha, Nirupam \| Supervisors: Haufe, Günter Period of time: until 05/02/2010 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Metathese von Vinylfluoriden: Ein vielseitiges Werkzeug zur Darstellung monofluorierter Heterocyclen und Alkaloidgerüste Candidate: Stillig, Christian \| Supervisors: Haufe, Günter Period of time: until 22/01/2010 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Neue fluorierte Aminosäurederivate und Aminohydroxamsäurederivate als Matrix-Metalloproteinase Inhibitoren Candidate: Behrends, Malte \| Supervisors: Haufe, Günter Period of time: until 12/10/2009 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

Professor Dr. Günter Haufe

Curriculum Vitae (CV)

Academic Education

Work Experience

Functions and Memberships

Appointments

Publications

Projects

Prizes

Doctorates

Contact

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