Leukocyte extravasation is subject to tight control and requires a delicate balance between pro- and anti-inflammatory signals for the correct initiation and termination of leukocyte activation and migration. In this project, we identify and characterize endogenous factors that control the extent of inflammatory leukocyte activation. A focus is on the anti-inflammatory protein Annexin A1 and its receptors of the formyl peptide receptor (FPR) family.
Gerke, Volker | Institute of Medical Biochemistry |
Rescher, Ursula | Institute of Medical Biochemistry |
Gerke, Volker | Institute of Medical Biochemistry |
Rescher, Ursula | Institute of Medical Biochemistry |