University of Münster
CRIS@UM
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Professur für Pharmazeutische Chemie (Prof. Müller)

Status: Organisation is ended
Address: 
Corrensstraße 48
48149 Münster
Germany

Publications

10-(4-Phenylpiperazine-1-carbonyl)acridin-9(10H)-ones and related compounds: Synthesis, antiproliferative activity and inhibition of tubulin polymerization
Waltemate J., Ivanov I., Ghasemi J. B., Aghaee E., Daniliuc C. G., Müller K., Prinz H. (2021)
In: Bioorganic and Medicinal Chemistry Letters, 32.
Research article (journal) | Peer reviewed | Published
A promising naphthoquinone [8-hydroxy-2-(2-thienylcarbonyl)naphtho[2,3-b]thiophene-4,9-dione] exerts anti-colorectal cancer activity through ferroptosis and inhibition of MAPK signaling pathway based on RNA sequencing
Caro D, Rivera, D. E., Ocampo Y., Müller K., Franco, L. A. (2020)
In: Open Chemistry, 18, 1242-1255.
Research article (journal) | Peer reviewed | Published
Synthesis, antiproliferative activity evaluation and 3D-QSAR study of naphthoquinone derivatives as potential anti-colorectal cancer agents
Acuña, J Piermattey, J Caro, D Barrios, L Bannwitz, S López, J Ocampo, Y Vivas-Reyes, R Gaitán, R Aristizábal, F Müller, K Franco, L (2018)
In: Molecules, 23. doi:10.3390/molecules23010186
Research article (journal) | Peer reviewed | Published
Napabucasin and Related Heterocycle-Fused Naphthoquinones as STAT3 Inhibitors with Antiproliferative Activity against Cancer Cells
Löcken H, Clamor C, Müller K  (2018)
In: Journal of Natural Products, 81(7), 1636-1644. doi:10.1021/acs.jnatprod.8b00247
Research article (journal) | Peer reviewed | Published
Oxadiazole-substituted naphtho[2,3-b]thiophene-4,9-diones as potent inhibitors of keratinocyte hyperproliferation. Structure−activity relationships of the tricyclic quinone skeleton and the oxadiazole substituent
Basoglu A, Dirkmann S, Zahedi Golpayegani N, Vortherms S, Tentrop J, Nowottnik D, Prinz H, Fröhlich R, Müller K (2017)
In: European Journal of Medicinal Chemistry, 134, 119-132. doi:10.1016/j.ejmech.2017.03.084
Research article (journal) | Peer reviewed | Published
Show all publications (130)

Projects

Niedermolekulare Effektoren des Zytoskeletts
Duration: 01/01/2004 - 31/12/2006
Funded by: Wirtschaft
Type of project: Individual project

Promotionen

Enantioselective Synthesis, Pharmacokinetic and Pharmacological Evaluation of Fused Heterocyclic Eutomers of -Opioid and GluN2B Sub-unit-Containing NMDA…
Candidate: Obeng-Darko, Henry | Supervisors: Wünsch, Bernhard | Reviewers: Wünsch, Bernhard; Müller, Klaus
Period of time: 01/10/2018 - 28/11/2022
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
In Vitro Functional Pharmacological Evaluation of Ligands at Purinergic Targets
Candidate: Isaak, Andreas | Supervisors: Junker, Anna; Wünsch, Bernhard, | Reviewers: Junker, Anna; Wünsch, Bernhard
Period of time: 01/05/2018 - 04/10/2022
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Synthese angular anellierter Analoga des Napabucasins und biologische Prüfung der antileishmaniellen Aktivität
Candidate: Kaske, Nino | Supervisors: Müller, Klaus
Period of time: 02/11/2017 - 22/03/2021
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
10-(4-Phenylpiperazin-1-carbonyl)acridin-9(10H)-one und verwandte Strukturen als neue Inhibitoren der Tubulinpolymerisation
Candidate: Waltemate, Jana | Supervisors: Müller, Klaus Prinz, Helge
Period of time: 02/05/2018 - 12/03/2021
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Synthese und vergleichende Untersuchungen von heterozyklisch anellierten Naphthochinonen und deren Prüfung als potenzielle Wirkstoffe der Tumortherapie
Candidate: Bernemann, Clemens Paul | Supervisors: Müller, Klaus
Period of time: 01/12/2016 - 22/01/2020
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Show all doctorates (45)

Parent organisational units