Deoxyestrone-based lipofection agents with solution- and solid-state emission properties
Huber A.; Koch J.; Rudolph K.; Höing A.; Rizzo F.; Knauer S.K.; Voskuhl J.
Research article (journal) | Peer reviewedAbstract
In this contribution, three deoxyestrone-based emissive lipofection agents are reported. Because of a centrally incorporated terephthalonitrile motif, these ligands can be classified as solution and solid-state emitters (SSSEs). With the attachment of tobramycin, these amphiphilic structures are able to form lipoplexes, mediating gene transfection of HeLa and HEK 293T cells.
Details about the publication
Journal: Organic and Biomolecular Chemistry (Org Biomol Chem)
Volume: 21
Issue: 28
Page range: 5762-5767
Status: Published
Release year: 2023
Language in which the publication is written: English
DOI: 10.1039/d3ob00656e
Link to the full text: https://api.elsevier.com/content/abstract/scopus_id/85165240023
Keywords: gene transfection; emissive dyes; deoxyestrone; HeLa cell; HEK 293T cell; solid state emitter
Authors from the University of Münster
| Rizzo, Fabio | Junior research group Fabio Rizzo |