Modulating the G-Quadruplex and Duplex DNA Binding by Controlling the Charge of Fluorescent Molecules
Gil-Martínez, Ariadna; López-Molina, Sònia; Galiana-Roselló, Cristina; Lázaro-Gómez, Andrea; Schlüter, Friederike; Rizzo, Fabio; González-García, Jorge
Research article (journal) | Peer reviewedAbstract
Two fluorescent and non-toxic spirobifluorene molecules being either positive (Spiro-NMe3) or negative (Spiro-SO3) charged have been investigated as DNA binders. Both molecules show a moderate binding to G-quadruplex and duplex DNA structures whereas the interaction is governed by the overall charge of the ligands.
Details about the publication
Journal: Chemistry - A European Journal (Chem. Eur. J.)
Volume: 29
Issue: 6
Article number: e202203094
Status: Published
Release year: 2023
Language in which the publication is written: English
Link to the full text: https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202203094
Keywords: duplex DNA; fluorescence; G-quadruplex; spirobifluorene; triphenylamine
Authors from the University of Münster
| Rizzo, Fabio | Junior research group Fabio Rizzo Center for Soft Nanoscience |
| Schlüter, Friederike | Center for Soft Nanoscience |