Modulating the G-Quadruplex and Duplex DNA Binding by Controlling the Charge of Fluorescent Molecules
Gil-Martínez, Ariadna; López-Molina, Sònia; Galiana-Roselló, Cristina; Lázaro-Gómez, Andrea; Schlüter, Friederike; Rizzo, Fabio; González-García, Jorge
Forschungsartikel (Zeitschrift) | Peer reviewedZusammenfassung
Two fluorescent and non-toxic spirobifluorene molecules being either positive (Spiro-NMe3) or negative (Spiro-SO3) charged have been investigated as DNA binders. Both molecules show a moderate binding to G-quadruplex and duplex DNA structures whereas the interaction is governed by the overall charge of the ligands.
Details zur Publikation
Fachzeitschrift: Chemistry - A European Journal (Chem. Eur. J.)
Jahrgang / Bandnr. / Volume: 29
Ausgabe / Heftnr. / Issue: 6
Artikelnummer: e202203094
Status: Veröffentlicht
Veröffentlichungsjahr: 2023
Sprache, in der die Publikation verfasst ist: Englisch
Link zum Volltext: https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202203094
Stichwörter: duplex DNA; fluorescence; G-quadruplex; spirobifluorene; triphenylamine
Autor*innen der Universität Münster
| Rizzo, Fabio | Nachwuchsforschungsgruppe Fabio Rizzo Center for Soft Nanoscience (SoN) |
| Schlüter, Friederike | Center for Soft Nanoscience (SoN) |