Mice lacking Wnt9a or Wnt4 are prone to develop spontaneous osteoarthritis with age and display alteration in either the trabecular or cortical bone compartment.

Teufel, Stefan; Wolff, Lena; König, Ulrich; Kobayashi, Akio; Behringer, Richard; Hartmann, Christine

Research article (journal) | Peer reviewed

Details about the publication

Journal: Journal of Bone and Mineral Research

Volume: 37

Issue: 7

Page range: 1335-1351

Status: Published

Release year: 2022

Keywords: Wnt9a; Wnt4; Osteoarthritis; Osteoporosis; trabecular bone; cortical bone

Hartmann, Christine	Institute of Musculoskeletal Medicine (IMM)
Teufel, Stefan	Institute of Musculoskeletal Medicine (IMM)
Wolff, Lena Ingeborg	Institute of Musculoskeletal Medicine (IMM)

Analyse der Rolle der Wnt-Liganden Wnt9a und Wnt4 in Knochen- und Gelenkshomeostase adulter Mäuse Duration: 01/09/2017 - 30/06/2021 Funded by: DFG - Individual Grants Programme Type of project: Individual project
Modified Wnt-signaling and its effects on degenerative and inflammatory joint alterations Duration: 01/01/2014 - 31/10/2017 Funded by: Interdisciplinary Center for Clinical Research Münster Type of project: Internally at the University of Münster funded project