Acylated 1H-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action

Korff M, Imberg L, Will JM, Buckreis N, Kalinina SA, Wenzel BM, Kastner GA, Daniliuc CG, Barth M, Ovsepyan RA, Butov KR, Humpf HU, Lehr M, Panteleev MA, Poso A, Karst U, Stenmetzer T, Bendas G, Kalinin DV

Research article (journal) | Peer reviewed

Details about the publication

JournalJournal of Medicinal Chemistry (J Med Chem)
Volume63
Issue21
Page range13159-13186
StatusPublished
Release year2020
Language in which the publication is writtenEnglish
DOI10.1021/acs.jmedchem.0c01635

Authors from the University of Münster

Humpf, Hans-Ulrich
Professur für Lebensmittelchemie (Prof. Humpf)
Imberg, Lukas
Professur für Pharmazeutische Chemie (Prof. Wünsch)
Kalinina, Svetlana
Professur für Lebensmittelchemie (Prof. Humpf)
Karst, Uwe
Professur für Analytische Chemie (Prof. Karst)
Korff, Marvin
Professur für Pharmazeutische Chemie (Prof. Wünsch)
Will, Jonas Maurice
Professur für Analytische Chemie (Prof. Karst)