Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.
Zhao, Xiaocheng, Nedvetsky, Pavel, Stanchi, Fabio, Vion, Anne-Clémence, Popp, Oliver, Zühlke, Kerstin, Dittmar, Gunnar, Klussmann, Enno, Gerhardt, Holger
Research article (journal) | Peer reviewedDetails about the publication
Journal: eLife
Volume: 8
Issue: The cAMP-dependent protein kinase A (PKA) regulates various cellular functions in health and disease. In endothelial cells PKA activity promotes vessel maturation and limits tip cell formation. Here, we used a chemical genetic screen to identify endothelia
Status: Published
Release year: 2019
DOI: 10.7554/elife.58195
Keywords: angiogenesis, PKA, cAMP, autophagy
Authors from the University of Münster
| Nedvetsky, Pavel |