Metal-mediated DNA assembly with ligand-based nucleosides
Mandal S, Müller J
Research article (journal) | Peer reviewedAbstract
Nucleic acids such as DNA are increasingly being applied in nanotechnology, as a result of their capability to self-assemble reversibly. The formal replacement of canonical base pairs by metal-mediated ones enables a site-specific introduction of metal-based functionality into these biomolecules, leading to the formation of predesigned metal arrays. This article offers an overview of structural aspects of metal-mediated base pairs, reviews recent advances in the field of metal-mediated base pairing and presents potential applications of the resulting metal-modified nucleic acids. It particularly focuses on recently developed metal-mediated base pairs with purine-derived nucleosides, gives an overview of metal-responsive systems relying on metal-mediated base pairs and summarizes various applications beyond metal-ion sensors.
Details about the publication
Authors from the University of Münster
| Mandal, Soham | Professorship of Inorganic Chemistry (Prof. Müller) |
| Müller, Jens | Professorship of Inorganic Chemistry (Prof. Müller) |
Projects the publication originates from
Duration: 01/01/2010 - 31/12/2017 | 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster | |
NRW Research School "Molecules and Materials – A Common Design Principle" (Molecules and Materials) Duration: 01/10/2009 - 31/10/2012 Funded by: Federal Ministry of Culture and Science of the Federal State of North Rhine-Westphalia Type of project: Individual project |
Promotionen, aus denen die Publikation resultiert
| Metal-Mediated Base Pairs with Ethenoadenine, a Versatile Nucleobase Surrogate Candidate: Mandal, Soham | Supervisors: Müller, Jens Period of time: 08/10/2012 - 16/08/2016 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster |