CRC 858 B09 - Influence of consecutive metal-mediated base pairs in DNA double helices on charge transfer through DNA and other cooperative effects in metal-modified DNA (SFB 858)
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/01/2010 - 31/12/2017 | 2nd Funding period
Description
The DNA molecule represents also the key compound within project B9. On the basis of artificial metal-mediated base pairs with known geometry, we intend to generate and characterize double helices with a structure analogous to that suggested for M-DNA. We will study the influence of the artificial base pairs on charge transfer through the DNA helix. Based on sequences originally investigated for non-modified DNA, we will subsequently replace the natural base pairs by artificial metal-mediated ones and analyze a potential correlation between the efficiency of the charge transfer and the number and position of the incorporated metal ions. Both hole transfer and excess electron transfer will be studied.
Keywords: DNA; metal-mediated base pairs; double helices; charge transfer; electron transfer; hole transfer
Website of the project: http://www.uni-muenster.de/SFB858/
Funding identifier: INST 211/519-1:1
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Müller, Jens | Professorship of Inorganic Chemistry (Prof. Müller) |
Applicants from the University of Münster
| Müller, Jens | Professorship of Inorganic Chemistry (Prof. Müller) |
Research associates from the University of Münster
| Tebben, Ludger | Professur für Organische Chemie (Prof. Studer) |