D2.12 Report on workshop and recommendations highlighting the status of the information and identifying non-standard areas. Recommendations for research agenda going forward.

Krenn L, Kopp B, Sheridan H, Marmann A, Ignatova S, Sutherland I, Proksch P, Simmonds M, Sendker J

Abstract

The deliverable (i) takes up problems and non-standard areas that had been previously identified in the D2.10, (ii) discusses their relevance for CHM research, (iii) gives recommendations towards good practice and (iv) addresses particular issues for a research agenda. The most relevant topics are the widely unknown impact of TCM-specific post-harvest treatments on the composition of traditional extracts and the interactions between different herbal drugs in co-extracted multiple component mixtures. Analysis of metabolic fingerprints by multivariate statistics supervised by activity data is suggested as a promising approach to identify the chemical entities responsible for a preparations bioactivity, taking advantage of the rich variability offered by the complex traditional processing techniques. Knowledge about the chemistry responsible for a traditional preparation's activity is an essential prerequisite for the reasonable development of modernised and more convenient application forms.

Projects the publication originates from