Regioselectivity of the C-Metalation of 6-Furylpurine: Importance of Directing Effects
Sinha I, Hepp A, Schirmer B, Kösters J, Neugebauer J, Müller J
Research article (journal) | Peer reviewedAbstract
We report the C-metalation of 6-furylpurine with Pt2+, Pd2+, and Hg2+. The ligand binds the metal ions in a bidentate fashion, involving the N7 purine atom and one of the furyl carbon atoms. The regioselectivity is determined by the metal ion. Pt2+ and Pd2+ coordinate the furyl moiety in its β position and Hg2+ in its electronically preferred α position.
Details about the publication
Journal: Journal of the American Chemical Society (J. Am. Chem. Soc.)
Volume: 54
Page range: 4183-4185
Status: Published
Release year: 2015 (22/04/2015)
Language in which the publication is written: English
Link to the full text: http://dx.doi.org/10.1021/acs.inorgchem.5b00450
Authors from the University of Münster
| Hepp, Alexander | |
| Müller, Jens | |
| Neugebauer, Johannes | |
| Sinha, Indranil |