CRC 656 B07 - Mathematical Modelling of Atherosclerotic Plaque Formation Based on Data from Multiparametric Imaging

Basic data for this project

Type of projectSubproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster01/07/2013 - 30/06/2017 | 1st Funding period

Description

Most vascular pathologies arise from atherosclerosis. Atherogenesis is an inflammatory process mainly triggered by low-density lipoproteins entering the intimal layer of arteries. This phenomenon in turn is regionally related to a blood flow dependent change in endothelial shear stress. We aim at numerical modeling of atherogenesis based on multiparametric imaging data of vessel architecture, blood flow and vascular inflammation. Simulation-based characterisation of the dependence of plaque formation on critical parameters should finally support our understanding of plaque development.

KeywordsMathematical Modelling; Atherosclerotic Plaque; Multiparametric Imaging
DFG-Gepris-IDhttps://gepris.dfg.de/gepris/projekt/241953848
Funder / funding scheme
  • DFG - Collaborative Research Centre (SFB)

Project management at the University of Münster

Ohlberger, Mario
Wierling, Stefan

Applicants from the University of Münster

Ohlberger, Mario

Research associates from the University of Münster

Meyer, Falk
Wierling, Stefan

Related main project

Duration: 01/07/2005 - 30/06/2017 | 1st Funding period
Funded by: DFG - Collaborative Research Centre
Type of project: Main DFG-project hosted at University of Münster

Publications of the University of Münster resulting from the project

Girke S, Klöfkorn R, Ohlberger M (2014)
In: Fuhrmann J, Ohlberger M, Rohde C (eds.), Finite Volumes for Complex Applications VII-Elliptic, Parabolic and Hyperbolic Problems617-625Springer International Publishing. doi:10.1007/978-3-319-05591-6_61
Research article in edited proceedings (conference) | Peer reviewed | Published

Talks about the project

The Dune-Fem-DG module – towards a unified multiphysics framework –
Malkmus, Tobias; Girke, Stefan (08/07/2016)
PDESoft 2016, Warwick
Type of talk: scientific Talk
Efficient Numerical Modeling of Atherosclerotic Plaque Formation
Girke, Stefan (02/10/2015)
Molecular Imaging School - MIS 2015, Wien
Type of talk: scientific Talk
Atherosclerosis, Multiphysics and DUNE-FEM-DG
Girke, Stefan (28/09/2015)
Dune User Meeting 2015, Heidelberg
Type of talk: scientific Talk
Efficient Parallel Simulation of Atherosclerotic Plaque Formation Using Higher Order Discontinuous Galerkin Schemes
Girke, Stefan (23/06/2015)
I.R.I.S., Bergen
Type of talk: scientific Talk
Mathematical Modeling and Simulation of Atherosclerotic Plaque Formation
Girke, Stefan (03/03/2015)
Skiseminar 2015, Kleinwalsertal
Type of talk: scientific Talk
Show all talks (7)