Most vascular pathologies arise from atherosclerosis. Atherogenesis is an inflammatory process mainly triggered by low-density lipoproteins entering the intimal layer of arteries. This phenomenon in turn is regionally related to a blood flow dependent change in endothelial shear stress. We aim at numerical modeling of atherogenesis based on multiparametric imaging data of vessel architecture, blood flow and vascular inflammation. Simulation-based characterisation of the dependence of plaque formation on critical parameters should finally support our understanding of plaque development.
| Ohlberger, Mario | |
| Wierling, Stefan |
| Ohlberger, Mario |
| Meyer, Falk | |
| Wierling, Stefan |
Duration: 01/07/2005 - 30/06/2017 | 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster |
Girke S, Klöfkorn R, Ohlberger M (2014) In: Fuhrmann J, Ohlberger M, Rohde C (eds.), Finite Volumes for Complex Applications VII-Elliptic, Parabolic and Hyperbolic Problems, 617-625. Springer International Publishing. doi:10.1007/978-3-319-05591-6_61 Research article in edited proceedings (conference) | Peer reviewed | Published |
| The Dune-Fem-DG module – towards a unified multiphysics framework – Malkmus, Tobias; Girke, Stefan (08/07/2016) PDESoft 2016, Warwick Type of talk: scientific Talk | |
| Efficient Numerical Modeling of Atherosclerotic Plaque Formation Girke, Stefan (02/10/2015) Molecular Imaging School - MIS 2015, Wien Type of talk: scientific Talk | |
| Atherosclerosis, Multiphysics and DUNE-FEM-DG Girke, Stefan (28/09/2015) Dune User Meeting 2015, Heidelberg Type of talk: scientific Talk | |
| Efficient Parallel Simulation of Atherosclerotic Plaque Formation Using Higher Order Discontinuous Galerkin Schemes Girke, Stefan (23/06/2015) I.R.I.S., Bergen Type of talk: scientific Talk | |
| Mathematical Modeling and Simulation of Atherosclerotic Plaque Formation Girke, Stefan (03/03/2015) Skiseminar 2015, Kleinwalsertal Type of talk: scientific Talk |