CRC 656 C07 - Imaging of Transplant Vasculitis (SFB 656 C07)
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/07/2009 - 30/06/2017 | 2nd Funding period
Description
Nowadays, acute rejection (AR) can only be definitively diagnosed by renal biopsy. However, biopsies carry a risk of renal transplant injury and loss. The aim of this study is to study whether FDG-PET can detect AR in an allogeneic transplantation model and discriminate acute rejection from other models of acute kidney injury. By using functional and histological methods acute allograft rejection will be investigated in theses models and radioactive glucose (18F-FDG) as well as radioactive inhibitors of matrix metalloproteases and caspase-3 will be used as markers for detection of acute allograft rejection and follow-up after treatment.
Keywords: acute kidney injury
Website of the project: http://www.uni-muenster.de/Sfbmobil/projekte/organfunktion/c7.html
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Reuter, Stefan Johannes | Nephrological Institute |
| Schnöckel, Uta | Clinic for Nuclear Medicine |
Applicants from the University of Münster
| Reuter, Stefan Johannes | Nephrological Institute |
| Schnöckel, Uta | Clinic for Nuclear Medicine |