Clinic for Nuclear Medicine

Status: Organisation is active

Phone number: +49 251 83-47362

Fax number: +49 251 83-47363

Email address: nuklear@uni-muenster.de

Website: https://www.ukm.de/kliniken/nuklearmedizin

Address:

Albert-Schweitzer-Campus 1

48149 Münster

Germany

Publications

Synthesis of piperazine-based fluorinated fibroblast activation protein inhibitors for the development of a novel 18F-labeled PET imaging probe. Köchel R; Wagner S; Schwegmann K; Schäfers M; Breyholz HJ; Wünsch B (2025) In: European Journal of Medicinal Chemistry, 290, 117513-117513. doi:10.1016/j.ejmech.2025.117513 Research article (journal) \| Peer reviewed \| Published
Naphtho[1,2-b][1,4]diazepinedione-based P2X4 Receptor Antagonists from Structure-Activity Relationships Studies toward PET Tracer Development Erlitz, KS; Prinz, AK; Wagner, S; Massa, J; Dunker, C; Höhl, M; Griep, A; McMaus, RM; Schelhaas, S; Koch, O; Junker, A (2025) In: Journal of Medicinal Chemistry, 68, 6965-7002. doi:10.1021/acs.jmedchem.4c02171 Research article (journal) \| Peer reviewed \| Published
Novel [18F]Fluorine-Based PET Tracers with Polar But Nonbasic Linkers to Image the Fibroblast Activation Protein in the Microenvironment of Tumors Köchel, Ricardo; Schwegmann, Katrin; Breyholz, Hans-Jörg; Schäfers, Michael; Wagner, Stefan; Wünsch, Bernhard (2025) In: Journal of Medicinal Chemistry, 68(15), 16331-16348. doi:10.1021/acs.jmedchem.5c01228 Research article (journal) \| Peer reviewed \| Published
Basal Cell Carcinoma of the Head With Intense [68Ga]OncoFAP Uptake Ventura D, Ernst I, Timma B, Schäfers M, Backhaus P (2025) In: Clinical Nuclear Medicine, 1(50(3)), e182-e183. doi:10.1097/RLU.0000000000005595 Research article (journal) \| Peer reviewed \| Published
Toxicities of radioligand and radioisotope therapy in prostate cancer: a systematic review and meta-analysis Ventura D, Noto B, Jauregui NR, Roll W, Rahbar K (2025) In: Current Opinion in Urology, 1(35(4)), 572-480. doi:10.1097/MOU.0000000000001300 Research article (journal) \| Peer reviewed \| Published

Show all publications (577)

Projects

CRC 1450 - A01: Cell-type specific multiscale imaging of leukocytes through the combination of protein tagging and radiochemical labelling Duration: 01/01/2025 - 31/12/2028 \| 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
CRC 1450 - A04: Metabolic targeting of bacteria through complex carbohydrates and siderophores Duration: 01/01/2025 - 31/12/2028 \| 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
CRC 1450 - B06: Dynamic PET-MRI for integrated quantification of molecular immune responses and their vascular consequences Duration: 01/01/2025 - 31/12/2028 \| 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
CRC 1450 - C01: Metabolic priming of monocytes during inflammation in vivo Duration: 01/01/2025 - 31/12/2028 \| 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
KFO 342 - P8: The Renin-Angiotensin II Axis: a Novel Target for the Treatment of Acute Kidney Injury Duration: 01/10/2023 - 30/09/2026 \| 2nd Funding period Funded by: DFG - Clinical Research Unit Type of project: Subproject in DFG-joint project hosted at University of Münster

Show all projects (51)

Preisverleihungen

Preis der Deutschen Hochschulmedizin 2025 Awarded by: Deutsche Hochschulmedizin e.V. Award given to: Rahbar, Kambiz; Announced at: 28/10/2025 \| Date of awarding: 28/10/2025 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Ärzteliste 2022 Awarded by: BurdaVerlag Data Publishing GmbH Award given to: Baune, Bernhard; Beule, Achim; Bleckmann, Annalen; Brand, Eva; Brehler, Randolf; Bürklein, Sebastian; Eckardt, Lars; Ehmke, Benjamin; Eich, Hans Theodor; Eter, Nicole; Föll, Dirk; Gabriëls, Gert; Görge, Tobias; Heindel, Walter L.; Hirsch, Tobias; Hohoff, Ariane; Kleinheinz, Johannes; Kliesch, Sabine; Langer, Martin; Lenz, Georg; Lenz, Philipp; Malec, Edward Józef; Martens, Sven; Oberhuber, Alexander; Ochman, Sabine; Otte, Britta; Pascher, Andreas; Pavenstädt, Hermann-Joseph; Pöpping, Daniel; Raschke, Michael J.; Reinecke, Holger; Rijcken, Emile Marie; Rödl, Robert; Rudack, Claudia; Rutsch, Frank; Schäfer, Edgar; Schäfer, Sebastian; Schäfers, Michael; Schrader, Andres Jan; Semjonow, Axel; Stamm, Thomas; Stummer, Walter; Vogt, Björn; Wiendl, Heinz Siegfried; Zitzmann, Michael Announced at: 17/06/2022 \| Date of awarding: 17/06/2022 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Klinikliste 2021 Awarded by: BurdaVerlag Data Publishing GmbH Award given to: Institut für Genetik von Herzerkrankungen; Klinik für Allgemein-, Viszeral- und Transplantationschirurgie; Klinik für Allgemeine Orthopädie und Tumororthopädie; Klinik für Augenheilkunde; Klinik für Frauenheilkunde und Geburtshilfe; Klinik für Hals-, Nasen- und Ohrenheilkunde; Klinik für Hautkrankheiten -Allgemeine Dermatologie und Venerologie-; Klinik für Kardiologie I: Koronare Herzkrankheit, Herzinsuffizienz und Angiologie; Klinik für Kardiologie II: Rhythmologie; Klinik für Kardiologie III: Angeborene Herzfehler (EMAH) und Klappenerkrankungen; Klinik für Neurochirurgie; Klinik für Neurologie mit Institut für Translationale Neurologie; Klinik für Nuklearmedizin; Klinik für Psychische Gesundheit; Klinik für Psychosomatik und Psychotherapie; Klinik für Strahlentherapie -Radioonkologie-; Klinik für Unfall-, Hand- und Wiederherstellungschirurgie; Klinik für Urologie und Kinderurologie; Klinik für Vaskuläre und Endovaskuläre Chirurgie; Medizinische Klinik A; Zentrum für Zahn-, Mund- und Kieferheilkunde Announced at: 21/10/2021 \| Date of awarding: 21/10/2021 Type of distinction: Research award or other distinction
Forschungsförderpreis 2021 Awarded by: Maria-Möller-Stiftung Award given to: Ernsting, Jan; Hahn, Tim; Seifert, Robert Announced at: 07/06/2021 \| Date of awarding: 07/06/2021 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Ärzteliste 2021 Awarded by: BurdaVerlag Data Publishing GmbH Award given to: Baune, Bernhard; Beule, Achim; Bleckmann, Annalen; Brand, Stefan-Martin; Brand, Eva; Brehler, Randolf; Bürklein, Sebastian; Eckardt, Lars; Ehmke, Benjamin; Eich, Hans Theodor; Eter, Nicole; Föll, Dirk; Freisinger, Eva; Görge, Tobias; Heindel, Walter L.; Heuft, Gereon; Hohoff, Ariane; Kleinheinz, Johannes; Kliesch, Sabine; Klockenbusch, Walter; Langer, Martin; Lenz, Philipp; Malec, Edward Józef; Martens, Sven; Ochman, Sabine; Otte, Britta; Pascher, Andreas; Pavenstädt, Hermann-Joseph; Pöpping, Daniel; Raschke, Michael J.; Reinecke, Holger; Rijcken, Emile Marie; Rödl, Robert; Rudack, Claudia; Schäfer, Sebastian; Schäfer, Edgar; Schäfers, Michael; Schliemann, Benedikt; Schrader, Andres Jan; Schulze-Bahr, Eric; Semjonow, Axel; Stamm, Thomas; Stummer, Walter; Vogt, Björn; Warnecke, Tobias; Wiendl, Heinz Siegfried; Zitzmann, Michael Announced at: 01/06/2021 \| Date of awarding: 01/06/2021 Type of distinction: Research award or other distinction

Show all awards (30)

Promotionen

Der Einfluss der PET-Information auf die Zielvolumendefinition bei Gliomen Candidate: Schnittker, Sebastian \| Supervisors: Eich, Hans; Schäfers, Michael Period of time: until 30/10/2015 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Evaluation der 4 D list mode PET/CT basierten ESRT anhand von Phantommessung, Bestrahlungsplanung und Cone Beam CT Candidate: Eschrich, Yvonne \| Supervisors: Eich, Hans; Schäfers, Michael Period of time: until 11/06/2015 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Discovery of coronary plaque rupture and thrombus formation in a transgenic mouse model of diet-induced spontaneous myocardial death Candidate: Starsichova, Andrea \| Supervisors: Schäfers, Michael; Herzog, Wiebke; Gerke, Volker Period of time: 09/10/2009 - 08/02/2013 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
PET surveillance of patients with Ewing sarcomas of the trunk: Must the lower legs be included? Candidate: Vrachimis, Alexis \| Supervisors: Weckesser, Matthias; Schober, Otmar; Dirksen, Uta Period of time: 01/06/2009 - 01/07/2011 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Evaluation and Comparison of 11C-Choline Uptake and Calcification in Aortic and Common Carotid Arterial Walls with Combined PET/CT Candidate: Stegger, Lars \| Supervisors: Schäfers, Michael Period of time: until 06/12/2010 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

Show all doctorates (15)

Habilitationen

Entzündungsdiagnostik in der Nuklearmedizin: Von der Fluordesoxyglukose zu innovativen Tracern und neuen Methoden Candidate: Roll, Wolfgang Michael \| Reviewers: Faber, Cornelius Period of time: until 26/10/2021 Habilitation procedure finished at: Habilitation procedure at University of Münster
Neue Strategien zur Radiomarkierung und Optimierung der Pharmakokinetik von Target-spezifischen Liganden zur molekularen Bildgebung Candidate: Hugenberg, Verena \| Reviewers: Faber, Cornelius Period of time: until 06/10/2020 Habilitation procedure finished at: Habilitation procedure at University of Münster
Erhöhung des klinischen Outcome durch personalisierte Strahlentherapie Candidate: Scobioala, Sergiu \| Reviewers: Schäfers, Michael Period of time: until 06/10/2020 Habilitation procedure finished at: Habilitation procedure at University of Münster
Enhancing diagnosis and risk stratification of cardiac involvement in a range of genetic myopathies by means of cardiovascular magnetic resonance imaging Candidate: Florian, Anca Rezeda \| Reviewers: Stegger, Lars Period of time: until 28/04/2020 Habilitation procedure finished at: Habilitation procedure at University of Münster
Translational Molecular Imaging of Inflammation Candidate: Hermann, Sven \| Reviewers: Roth, Johannes Period of time: until 17/04/2018 Habilitation procedure finished at: Habilitation procedure at University of Münster

Show all habilitations (22)

Vorträge

Scientists’ views on their own engagement in science communication and outreach activities
Hendriks, Frederike; Niederhoff, Doris; Kienhues, Dorothe; Bromme, Rainer (06/04/2018)
Paper presented at the 15th Public Communication of Science and Technology (PCST) Conference, Dunedin, New Zealand
Type of talk: scientific talk

Parent organisational units

University of Münster
- Schools and Faculties
  - FB05 - Faculty of Medicine
    - Center of Radiology

Synthesis of piperazine-based fluorinated fibroblast activation protein inhibitors for the development of a novel 18F-labeled PET imaging probe. Köchel R; Wagner S; Schwegmann K; Schäfers M; Breyholz HJ; Wünsch B (2025) In: European Journal of Medicinal Chemistry, 290, 117513-117513. doi:10.1016/j.ejmech.2025.117513 Research article (journal) \| Peer reviewed \| Published
Naphtho[1,2-b][1,4]diazepinedione-based P2X4 Receptor Antagonists from Structure-Activity Relationships Studies toward PET Tracer Development Erlitz, KS; Prinz, AK; Wagner, S; Massa, J; Dunker, C; Höhl, M; Griep, A; McMaus, RM; Schelhaas, S; Koch, O; Junker, A (2025) In: Journal of Medicinal Chemistry, 68, 6965-7002. doi:10.1021/acs.jmedchem.4c02171 Research article (journal) \| Peer reviewed \| Published
Novel [18F]Fluorine-Based PET Tracers with Polar But Nonbasic Linkers to Image the Fibroblast Activation Protein in the Microenvironment of Tumors Köchel, Ricardo; Schwegmann, Katrin; Breyholz, Hans-Jörg; Schäfers, Michael; Wagner, Stefan; Wünsch, Bernhard (2025) In: Journal of Medicinal Chemistry, 68(15), 16331-16348. doi:10.1021/acs.jmedchem.5c01228 Research article (journal) \| Peer reviewed \| Published
Basal Cell Carcinoma of the Head With Intense [68Ga]OncoFAP Uptake Ventura D, Ernst I, Timma B, Schäfers M, Backhaus P (2025) In: Clinical Nuclear Medicine, 1(50(3)), e182-e183. doi:10.1097/RLU.0000000000005595 Research article (journal) \| Peer reviewed \| Published
Toxicities of radioligand and radioisotope therapy in prostate cancer: a systematic review and meta-analysis Ventura D, Noto B, Jauregui NR, Roll W, Rahbar K (2025) In: Current Opinion in Urology, 1(35(4)), 572-480. doi:10.1097/MOU.0000000000001300 Research article (journal) \| Peer reviewed \| Published

CRC 1450 - A01: Cell-type specific multiscale imaging of leukocytes through the combination of protein tagging and radiochemical labelling Duration: 01/01/2025 - 31/12/2028 \| 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
CRC 1450 - A04: Metabolic targeting of bacteria through complex carbohydrates and siderophores Duration: 01/01/2025 - 31/12/2028 \| 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
CRC 1450 - B06: Dynamic PET-MRI for integrated quantification of molecular immune responses and their vascular consequences Duration: 01/01/2025 - 31/12/2028 \| 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
CRC 1450 - C01: Metabolic priming of monocytes during inflammation in vivo Duration: 01/01/2025 - 31/12/2028 \| 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
KFO 342 - P8: The Renin-Angiotensin II Axis: a Novel Target for the Treatment of Acute Kidney Injury Duration: 01/10/2023 - 30/09/2026 \| 2nd Funding period Funded by: DFG - Clinical Research Unit Type of project: Subproject in DFG-joint project hosted at University of Münster

Preis der Deutschen Hochschulmedizin 2025 Awarded by: Deutsche Hochschulmedizin e.V. Award given to: Rahbar, Kambiz; Announced at: 28/10/2025 \| Date of awarding: 28/10/2025 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Ärzteliste 2022 Awarded by: BurdaVerlag Data Publishing GmbH Award given to: Baune, Bernhard; Beule, Achim; Bleckmann, Annalen; Brand, Eva; Brehler, Randolf; Bürklein, Sebastian; Eckardt, Lars; Ehmke, Benjamin; Eich, Hans Theodor; Eter, Nicole; Föll, Dirk; Gabriëls, Gert; Görge, Tobias; Heindel, Walter L.; Hirsch, Tobias; Hohoff, Ariane; Kleinheinz, Johannes; Kliesch, Sabine; Langer, Martin; Lenz, Georg; Lenz, Philipp; Malec, Edward Józef; Martens, Sven; Oberhuber, Alexander; Ochman, Sabine; Otte, Britta; Pascher, Andreas; Pavenstädt, Hermann-Joseph; Pöpping, Daniel; Raschke, Michael J.; Reinecke, Holger; Rijcken, Emile Marie; Rödl, Robert; Rudack, Claudia; Rutsch, Frank; Schäfer, Edgar; Schäfer, Sebastian; Schäfers, Michael; Schrader, Andres Jan; Semjonow, Axel; Stamm, Thomas; Stummer, Walter; Vogt, Björn; Wiendl, Heinz Siegfried; Zitzmann, Michael Announced at: 17/06/2022 \| Date of awarding: 17/06/2022 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Klinikliste 2021 Awarded by: BurdaVerlag Data Publishing GmbH Award given to: Institut für Genetik von Herzerkrankungen; Klinik für Allgemein-, Viszeral- und Transplantationschirurgie; Klinik für Allgemeine Orthopädie und Tumororthopädie; Klinik für Augenheilkunde; Klinik für Frauenheilkunde und Geburtshilfe; Klinik für Hals-, Nasen- und Ohrenheilkunde; Klinik für Hautkrankheiten -Allgemeine Dermatologie und Venerologie-; Klinik für Kardiologie I: Koronare Herzkrankheit, Herzinsuffizienz und Angiologie; Klinik für Kardiologie II: Rhythmologie; Klinik für Kardiologie III: Angeborene Herzfehler (EMAH) und Klappenerkrankungen; Klinik für Neurochirurgie; Klinik für Neurologie mit Institut für Translationale Neurologie; Klinik für Nuklearmedizin; Klinik für Psychische Gesundheit; Klinik für Psychosomatik und Psychotherapie; Klinik für Strahlentherapie -Radioonkologie-; Klinik für Unfall-, Hand- und Wiederherstellungschirurgie; Klinik für Urologie und Kinderurologie; Klinik für Vaskuläre und Endovaskuläre Chirurgie; Medizinische Klinik A; Zentrum für Zahn-, Mund- und Kieferheilkunde Announced at: 21/10/2021 \| Date of awarding: 21/10/2021 Type of distinction: Research award or other distinction
Forschungsförderpreis 2021 Awarded by: Maria-Möller-Stiftung Award given to: Ernsting, Jan; Hahn, Tim; Seifert, Robert Announced at: 07/06/2021 \| Date of awarding: 07/06/2021 Type of distinction: Research award or other distinction
Aufnahme in die Focus-Ärzteliste 2021 Awarded by: BurdaVerlag Data Publishing GmbH Award given to: Baune, Bernhard; Beule, Achim; Bleckmann, Annalen; Brand, Stefan-Martin; Brand, Eva; Brehler, Randolf; Bürklein, Sebastian; Eckardt, Lars; Ehmke, Benjamin; Eich, Hans Theodor; Eter, Nicole; Föll, Dirk; Freisinger, Eva; Görge, Tobias; Heindel, Walter L.; Heuft, Gereon; Hohoff, Ariane; Kleinheinz, Johannes; Kliesch, Sabine; Klockenbusch, Walter; Langer, Martin; Lenz, Philipp; Malec, Edward Józef; Martens, Sven; Ochman, Sabine; Otte, Britta; Pascher, Andreas; Pavenstädt, Hermann-Joseph; Pöpping, Daniel; Raschke, Michael J.; Reinecke, Holger; Rijcken, Emile Marie; Rödl, Robert; Rudack, Claudia; Schäfer, Sebastian; Schäfer, Edgar; Schäfers, Michael; Schliemann, Benedikt; Schrader, Andres Jan; Schulze-Bahr, Eric; Semjonow, Axel; Stamm, Thomas; Stummer, Walter; Vogt, Björn; Warnecke, Tobias; Wiendl, Heinz Siegfried; Zitzmann, Michael Announced at: 01/06/2021 \| Date of awarding: 01/06/2021 Type of distinction: Research award or other distinction

Der Einfluss der PET-Information auf die Zielvolumendefinition bei Gliomen Candidate: Schnittker, Sebastian \| Supervisors: Eich, Hans; Schäfers, Michael Period of time: until 30/10/2015 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Evaluation der 4 D list mode PET/CT basierten ESRT anhand von Phantommessung, Bestrahlungsplanung und Cone Beam CT Candidate: Eschrich, Yvonne \| Supervisors: Eich, Hans; Schäfers, Michael Period of time: until 11/06/2015 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Discovery of coronary plaque rupture and thrombus formation in a transgenic mouse model of diet-induced spontaneous myocardial death Candidate: Starsichova, Andrea \| Supervisors: Schäfers, Michael; Herzog, Wiebke; Gerke, Volker Period of time: 09/10/2009 - 08/02/2013 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
PET surveillance of patients with Ewing sarcomas of the trunk: Must the lower legs be included? Candidate: Vrachimis, Alexis \| Supervisors: Weckesser, Matthias; Schober, Otmar; Dirksen, Uta Period of time: 01/06/2009 - 01/07/2011 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Evaluation and Comparison of 11C-Choline Uptake and Calcification in Aortic and Common Carotid Arterial Walls with Combined PET/CT Candidate: Stegger, Lars \| Supervisors: Schäfers, Michael Period of time: until 06/12/2010 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

Entzündungsdiagnostik in der Nuklearmedizin: Von der Fluordesoxyglukose zu innovativen Tracern und neuen Methoden Candidate: Roll, Wolfgang Michael \| Reviewers: Faber, Cornelius Period of time: until 26/10/2021 Habilitation procedure finished at: Habilitation procedure at University of Münster
Neue Strategien zur Radiomarkierung und Optimierung der Pharmakokinetik von Target-spezifischen Liganden zur molekularen Bildgebung Candidate: Hugenberg, Verena \| Reviewers: Faber, Cornelius Period of time: until 06/10/2020 Habilitation procedure finished at: Habilitation procedure at University of Münster
Erhöhung des klinischen Outcome durch personalisierte Strahlentherapie Candidate: Scobioala, Sergiu \| Reviewers: Schäfers, Michael Period of time: until 06/10/2020 Habilitation procedure finished at: Habilitation procedure at University of Münster
Enhancing diagnosis and risk stratification of cardiac involvement in a range of genetic myopathies by means of cardiovascular magnetic resonance imaging Candidate: Florian, Anca Rezeda \| Reviewers: Stegger, Lars Period of time: until 28/04/2020 Habilitation procedure finished at: Habilitation procedure at University of Münster
Translational Molecular Imaging of Inflammation Candidate: Hermann, Sven \| Reviewers: Roth, Johannes Period of time: until 17/04/2018 Habilitation procedure finished at: Habilitation procedure at University of Münster