The blood-brain barrier in Drosophila is made by a set of specialized septate junction forming cells that establish an endothelial-like sheet around the entire nervous system. We seek to understand the role of tricellular junctions for the dynamics of septate junction formation and their transient opening during inflammation. We previously demonstrated transmigration of macrophages across the Drosophila blood-brain barrier and will now determine the signals that lure the macrophages towards and into the nervous system.
| Klämbt, Christian |
| Klämbt, Christian |
Duration: 01/07/2016 - 30/06/2020 | 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster |
Duration: 01/07/2012 - 30/06/2016 | 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster |