CRC 1009 A04 - Analysis of the Drosophila blood brain barrier

Basic data for this project

Type of project: Subproject in DFG-joint project hosted at University of Münster

Duration at the University of Münster: 01/07/2016 - 30/06/2020 | 2nd Funding period

Description

The blood-brain barrier in Drosophila is made by a set of specialized septate junction forming cells that establish an endothelial-like sheet around the entire nervous system. We seek to understand the role of tricellular junctions for the dynamics of septate junction formation and their transient opening during inflammation. We previously demonstrated transmigration of macrophages across the Drosophila blood-brain barrier and will now determine the signals that lure the macrophages towards and into the nervous system.

Keywords: Drosophila glia; Blut-Hirn-Schranke

Website of the project: https://campus.uni-muenster.de/de/sfb-1009/projekte/projektbereich-a/a-04/

DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/222656448

Funding identifier: SFB 1009/2 | DFG project number: 194468054

Funder / funding scheme:

DFG - Collaborative Research Centre (SFB)

Project management at the University of Münster

Klämbt, Christian	Professorship of Neuro- and Behavioral Biology (Prof. Klämbt)
Luschnig, Stefan	Professorship for morphogenesis of tubular organs (Prof. Luschnig)

Applicants from the University of Münster

Klämbt, Christian	Professorship of Neuro- and Behavioral Biology (Prof. Klämbt)
Luschnig, Stefan	Professorship for morphogenesis of tubular organs (Prof. Luschnig)