CRC 1009 A10 - Regulation of blood-brain-barrier function by pericytes
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/07/2016 - 30/06/2020 | 1st Funding period
Description
The function of the blood-brain barrier relies on close interactions between different cell types including endothelial cells, pericytes and astrocytes. Here, we propose to study the role of the transcriptional coactivators YAP/TAZ and the Hippo signaling pathway in brain pericytes with cell type-specific and inducible genetic approaches in mice, cell biology, RNA sequencing, and biochemistry experiments. The planned work will provide important novel insights into the functional properties of pericytes and their role in the regulation of the blood-brain barrier.
Keywords: Endothelial cell biology
Website of the project: https://campus.uni-muenster.de/de/sfb-1009/projekte/projektbereich-a/a-10/
DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/320809837
Funding identifier: SFB 1009/2 | DFG project number: 194468054
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Adams, Ralf Heinrich |
Applicants from the University of Münster
| Adams, Ralf Heinrich |
Projects of the following funding period
Duration: 01/07/2020 - 30/06/2024 | 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster |
Related main project
Duration: 01/07/2016 - 30/06/2020 | 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster |