CRC 1009 B08 - DAMP-induced proinflammatory feedback mechanisms between phagocytes and endothelial / epithelial barriers in infectious diseases
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/07/2016 - 30/06/2020 | 2nd Funding period
Description
Pulmonary infectious diseases are often amplified by mechanisms induced by endogenous ligands (DAMPs). The interplay of DAMPs and PAMPs lead to the breakdown of endothelial and epithelial lung barriers and overwhelming immune responses causing severe complications in clinical practice. Goal of the follow-up research project B08 is to further elucidate the S100A8/A9-TLR4/MD2-DAMP mechanism and the implications for the lung epithelial barrier for the development of new therapeutic options against pulmonary diseases.
Keywords: Phagocyte biology; danger signalling
Website of the project: https://campus.uni-muenster.de/de/sfb-1009/projekte/projektbereich-b/b-08/
DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/222662725
Funding identifier: SFB 1009/2 | DFG project number: 194468054
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Projects of the previous funding period
Duration: 01/07/2012 - 30/06/2016 | 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster |
Projects of the following funding period
Duration: 01/07/2020 - 30/06/2024 | 3rd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster |
Related main project
Duration: 01/07/2016 - 30/06/2020 | 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster |