CRC 1009 B09 - Epidermal stress response and barrier integrity in allergy and autoimmune diseases
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/07/2016 - 30/06/2020 | 2nd Funding period
Description
The skin is one of the main immunological barriers sensing many different triggers from external microorganisms and tissue-derived signals. The goal of our research project is to analyse the S100-alarmin driven stress response during dermal inflammation in autoimmune diseases and allergies. We will analyse the time-, dose- and tissue-dependent effects of S100A8 and S100A9 on a molecular level with respect to their activating and regulatory functions on the skin immune system. Our approach will define new regulatory mechanisms of dermal inflammation which may point to novel molecular targets for future therapies.
Keywords: Innate immunity; autoimmune diseases
Website of the project: https://campus.uni-muenster.de/sfb-1009/projekte/projektbereich-b/b-09/
DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/222667230
Funding identifier: SFB 1009/2 | DFG project number: 194468054
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Roth, Johannes |
Applicants from the University of Münster
| Roth, Johannes |
Projects of the previous funding period
Duration: 01/07/2012 - 30/06/2016 | 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster |
Projects of the following funding period
Duration: 01/07/2020 - 30/06/2024 | 3rd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster |
Related main project
Duration: 01/07/2016 - 30/06/2020 | 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster |