EXC 1003 FF-2013-16 - PET imaging of freely moving mice

Basic data for this project

Type of projectSubproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster01/07/2013 - 30/06/2016 | 1st Funding period

Description

Positron Emission Tomography (PET) is a most sensitive imaging tool to study molecular metabolism in vivo. Due to the long acquisition time (minutes) of PET, anesthesia is widely used in small animal studies to avoid motion. However, impact of anesthesia on organ function depicted by PET studies was found to be significant. Therefore, the application of PET as a quantitative method to analyze spontaneous "natural" metabolism becomes critical or even impossible in anesthetized animal subjects. In this project we develop techniques and realize a system for freely moving mouse PET imaging based on the high-resolution small animal PET scanner quadHIDAC.

KeywordsPET scanner; molecular metabolism; biochemistry
Website of the projecthttp://www.uni-muenster.de/Cells-in-Motion/research/flexible-fund-projects/FF-2013-16.php
Funder / funding scheme
  • DFG - Cluster of Excellence (EXC)

Project management at the University of Münster

Jiang, Xiaoyi
Professur für Praktische Informatik (Prof. Jiang)
Schäfers, Klaus
European Institute of Molecular Imaging (EIMI)
Wübbeling, Frank
Institute for Analysis and Numerics

Applicants from the University of Münster

Schäfers, Klaus
European Institute of Molecular Imaging (EIMI)