EXC 1003 FF-2013-16 - PET imaging of freely moving mice

Basic data for this project

Type of project: Subproject in DFG-joint project hosted at University of Münster

Duration at the University of Münster: 01/07/2013 - 30/06/2016 | 1st Funding period

Description

Positron Emission Tomography (PET) is a most sensitive imaging tool to study molecular metabolism in vivo. Due to the long acquisition time (minutes) of PET, anesthesia is widely used in small animal studies to avoid motion. However, impact of anesthesia on organ function depicted by PET studies was found to be significant. Therefore, the application of PET as a quantitative method to analyze spontaneous "natural" metabolism becomes critical or even impossible in anesthetized animal subjects. In this project we develop techniques and realize a system for freely moving mouse PET imaging based on the high-resolution small animal PET scanner quadHIDAC.

Keywords: PET scanner; molecular metabolism; biochemistry

Website of the project: http://www.uni-muenster.de/Cells-in-Motion/research/flexible-fund-projects/FF-2013-16.php

Funder / funding scheme:

DFG - Cluster of Excellence (EXC)

Project management at the University of Münster

Jiang, Xiaoyi	Professur für Praktische Informatik (Prof. Jiang)
Schäfers, Klaus	European Institute for Molecular Imaging (EIMI)
Wübbeling, Frank	Institute for Analysis and Numerics

Applicants from the University of Münster

Schäfers, Klaus

European Institute for Molecular Imaging (EIMI)

Related main project

EXC 1003 Cells in Motion - Imaging to Understand Cellular Behaviour in Organisms (CIM)

Duration: 01/11/2012 - 31/10/2019 | 1st Funding period

Funded by: DFG - Cluster of Excellence

Type of project: Main DFG-project hosted at University of Münster