CRC 1348 A09 - Regulation and Execution of Vesicle Formation in WASH-mediated Endocytosis
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/01/2022 - 31/12/2025 | 2nd Funding period
Description
Tetraspanin-enriched microdomains (TEM) act as platforms in the plasma membrane regulating various biological processes. Depending on the composition of TEM, tetraspanins modulate, stabilize, or prevent the activities of associated molecules. In this project, we will analyze the role of the dynamic composition of TEM for induction and execution of a novel endocytic mechanism used by human papillomaviruses (HPV) for infection. In particular, we are interested in the recruitment of cellular factors regulating membrane bending and scission. Likewise, we aim to address the impact of endocytosis on the virus-induced, TEM-mediated signaling outcome.
Keywords: Biology; cellular interfaces; imaging modalities
Website of the project: http://sfb1348.uni-muenster.de/projects/a/project-a09
Funding identifier: SFB 1348/2 A09
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Schelhaas, Mario | Institute of Molecular Virology |
Applicants from the University of Münster
| Schelhaas, Mario | Institute of Molecular Virology |