SFB 1348 - A09: Regulation der Vesikel-Bildung während WASH-vermittelter Endozytose

Grunddaten zu diesem Projekt

Art des Projektes: Teilprojekt in DFG-Verbund koordiniert an der Universität Münster

Laufzeit an der Universität Münster: 01.01.2022 - 31.12.2025 | 2. Förderperiode

Beschreibung

Tetraspanin-enriched microdomains (TEM) act as platforms in the plasma membrane regulating various biological processes. Depending on the composition of TEM, tetraspanins modulate, stabilize, or prevent the activities of associated molecules. In this project, we will analyze the role of the dynamic composition of TEM for induction and execution of a novel endocytic mechanism used by human papillomaviruses (HPV) for infection. In particular, we are interested in the recruitment of cellular factors regulating membrane bending and scission. Likewise, we aim to address the impact of endocytosis on the virus-induced, TEM-mediated signaling outcome.

Stichwörter: Biologie; zelluläre Kontaktstellen; Bildgebung

Webseite des Projekts: http://sfb1348.uni-muenster.de/projects/a/project-a09

DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/394345406

Förderkennzeichen: SFB 1348/2 A09 | DFG-Projektnummer: 386797833

Mittelgeber / Förderformat: