CRC 1009 A04 - Analysis of the Drosophila blood-brain barrier

Basic data for this project

Type of projectSubproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster01/07/2020 - 30/06/2024 | 3rd Funding period

Description

The blood-brain barrier in Drosophila is made by a set of specialized septate junction forming cells that establish an endothelial-like sheet around the entire nervous system. We seek to understand the role of tricellular junctions for the dynamics of septate junction formation and their transient opening during inflammation. We previously demonstrated transmigration of macrophages across the Drosophila blood-brain barrier and will now determine the signals that lure the macrophages towards and into the nervous system.

KeywordsDevelopmental Biology; Neurobiology; Animal Physiology
Website of the projecthttps://www.medizin.uni-muenster.de/sfb-1009/projekte/projektbereich-a/a-04.html
DFG-Gepris-IDhttps://gepris.dfg.de/gepris/projekt/222656448
Funding identifierSFB 1009/3, A04 | DFG project number: 194468054
Funder / funding scheme
  • DFG - Collaborative Research Centre (SFB)

Project management at the University of Münster

Klämbt, Christian
Professorship of Neuro- and Behavioral Biology (Prof. Klämbt)
Luschnig, Stefan
Professorship for morphogenesis of tubular organs (Prof. Luschnig)
Schirmeier, Stefanie
Professorship of Neuro- and Behavioral Biology (Prof. Klämbt)

Applicants from the University of Münster

Klämbt, Christian
Professorship of Neuro- and Behavioral Biology (Prof. Klämbt)
Luschnig, Stefan
Professorship for morphogenesis of tubular organs (Prof. Luschnig)
Schirmeier, Stefanie
Professorship of Neuro- and Behavioral Biology (Prof. Klämbt)