CRC 1748 - A07: The genomic landscape of non-obstructive azoospermia
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/04/2026 - 31/12/2029 | 1st Funding period
Description
Although many azoospermia-related genes have been identified in recent years, most affected men still remain without a causal diagnosis, precluding personalised treatment. The molecular mechanisms underlying azoospermia will, therefore, be elucidated. To this end, the significance of NXT2-interacting proteins as well as the novel X-linked candidate genes TKTL1 and KIAA1210 in male infertility will be explored. Further, the MERGE cohort will be expanded and novel in silico approaches will be employed to identify additional candidate genes for follow up. The results will be translated back into clinical practice to improve care for men with infertility.
Keywords: Azoospermie
DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/574757938
Funding identifier: SFB 1748, A07 | DFG project number: 549467913
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Tüttelmann, Frank | Institute of Human Genetics |
Applicants from the University of Münster
| Tüttelmann, Frank | Institute of Human Genetics |