CRC TRR 422 - B04: Analysis of extracellular vesicles (EVs) in podocyte survival and intercellular communication
Basic data for this project
Type of project: Subproject in DFG-joint project hosted outside University of Münster
Duration at the University of Münster: 01/10/2025 - 30/06/2029 | 1st Funding period
Description
In contrast to other organs, there is minimal information on the importance of EV formation and release for podocyte homeostasis. Using Drosophila as a model system as well as kidney organoids and mice, we will characterize the production, release, and content of podocyte-derived EVs and investigate to what extent podocyte homeostasis is dependent on the release of small or large EVs and whether changes in EV secretion render podocytes more vulnerable to, or conversely, more resistant to injury.
Keywords: Nephrology; Cell Biology
DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/566104881
Funding identifier: TRR 422/1, B04 | DFG project number: 543604419
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Krahn, Michael | Medical Clinic of Internal Medicine D (Nephrology and Rheumatology) (Med D) |
Applicants from the University of Münster
| Krahn, Michael | Medical Clinic of Internal Medicine D (Nephrology and Rheumatology) (Med D) |
Project partners outside the University of Münster
- University Medical Center Hamburg-Eppendorf (UKE)Germany
Coordinating organisations outside the University of Münster
- University Hospital CologneGermany