Univ. Prof. Dr. Timo Strünker

Current affiliations

Institut für Reproduktions- und Regenerationsbiologie

Publications

Chemosensory signalling in human sperm is controlled by Ca2+ influx via CatSper and Ca2+ clearance via plasma membrane Ca2+ ATPases Herrmann, Leonie; Brenker, Christoph; Mittermair, Teresa; Bojovic, Vesna; Münchow, Jens; Zhu, W. Felix; Trugge, Carla; Fußhöller, David; Jikeli, Jan; Temme, Louisa; Kaupp, U. Benjamin; Strünker, Strünker (2025) In: British Journal of Pharmacology, 182(12). Research article (journal)
Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation Young S; Schiffer C; Wagner A; Patz J; Potapenko A; Herrmann L; Nordhoff V; Pock T; Krallmann C; Stallmeyer B; Röpke A; Kierzek M; Biagioni C; Wang T; Haalck L; Deuster D; Hansen JN; Wachten D; Risse B; Behre HM; Schlatt S; Kliesch S; Tüttelmann F; Brenker C; Strünker T (2024) In: Journal of Clinical Investigation, 134(1). Research article (journal)
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition. Dellin, Maurice; Rohrbeck, Ina; Asrani, Purva; Schreiber, Julian A; Ritter, Nadine; Glorius, Frank; Wünsch, Bernhard; Budde, Thomas; Temme, Louisa; Strünker, Timo; Stallmeyer, Birgit; Tüttelmann, Frank; Meuth, Sven G; Spehr, Marc; Matschke, Johann; Steinbicker, Andrea; Gatsogiannis, Christos; Stoll, Raphael; Strutz-Seebohm, Nathalie; Seebohm, Guiscard (2023) In: Journal of Biological Chemistry, 404(4). Research article (journal)
Pathogenic gene variants in CCDC39, CCDC40, RSPH1, RSPH9, HYDIN, and SPEF2 cause defects of sperm flagella composition and male infertility. Aprea, I; Wilken, A; Krallmann, C; Nöthe-Menchen, T; Olbrich, H; Loges, NT; Dougherty, GW; Bracht, D; Brenker, C; Kliesch, S; Strünker, T; Tüttelmann, F; Raidt, J; Omran, H (2023) In: Frontiers in Genetics, 14. Research article (journal)
HPLC fluorescence assay for measuring the activity of NAPE-PLD and the action of inhibitors affecting this enzyme. Lange, Thomas; Depmeier, Tim; Strünker, Timo; Lehr, Matthias (2023) In: Journal of Pharmaceutical and Biomedical Analysis, 229. Research article (journal)

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Projects

CRC 1748: Principles of Reproduction – Unravelling the Molecular Mechanisms of Male Infertility Duration: 01/04/2026 - 31/12/2029 \| 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster
CRC 1748 - B03: Molecular mechanisms of calcium signalling in human sperm Duration: 01/04/2026 - 31/12/2029 \| 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
CRC 1748 - RTG.MS: Integriertes Graduiertenkolleg "Reproduction.MS" Duration: 01/04/2026 - 31/12/2029 \| 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
Determining sperm in vitro-assay thresholds for male infertility Duration: 15/12/2024 - 30/06/2027 Funded by: Gates Foundation Type of project: Participation in other joint projects
RTG 2515: Chemical Biology of Ion Channels (Chembion) Duration: 01/04/2024 - 30/09/2028 \| 2nd Funding period Funded by: DFG - Research Training Group Type of project: Main DFG-project hosted at University of Münster

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Prizes

Münsterland Innovation Award in the category: Start-up (1st prize)
Awarded by: Münsterland e.V.
Award given to: Fischer, Vincent Lucas; Schiffer, Christian; Young, Samuel; Brenker, Christoph; Strünker, Timo
Announced at: 11/06/2024 | Date of awarding: 11/06/2024
Type of distinction: Research award or other distinction

Doctorates

Einfluss von Neuropeptid S im anterioren Nucleus paraventricularis thalami auf angeborene Ängstlichkeit und konditionierte Furcht unter Berücksichtigung der…
Candidate: Steinrücken, Jakob | Supervisors: Budde, Thomas; Strünker, Timo; Seidenbecher, Thomas | Reviewers: Budde, Thomas; Strünker, Timo
Period of time: 01/10/2019 - 01/10/2021
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

CRC 1748: Principles of Reproduction – Unravelling the Molecular Mechanisms of Male Infertility Duration: 01/04/2026 - 31/12/2029 \| 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster
CRC 1748 - B03: Molecular mechanisms of calcium signalling in human sperm Duration: 01/04/2026 - 31/12/2029 \| 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
CRC 1748 - RTG.MS: Integriertes Graduiertenkolleg "Reproduction.MS" Duration: 01/04/2026 - 31/12/2029 \| 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
Determining sperm in vitro-assay thresholds for male infertility Duration: 15/12/2024 - 30/06/2027 Funded by: Gates Foundation Type of project: Participation in other joint projects
RTG 2515: Chemical Biology of Ion Channels (Chembion) Duration: 01/04/2024 - 30/09/2028 \| 2nd Funding period Funded by: DFG - Research Training Group Type of project: Main DFG-project hosted at University of Münster