Dr. Kornelius Tobias Kerl

Current affiliations

University Children's Hospital - Department of Paediatric Haematology and Oncology (UKM PHO)

Publications

ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution de Faria, Flavia W.; Riedel, Nicole C.; Münter, Daniel; Interlandi, Marta; Göbel, Carolin; Altendorf, Lea; Richter, Mathis; Melcher, Viktoria; Thomas, Christian; Roy, Rajanya; Schoof, Melanie; Bedzhov, Ivan; Moreno, Natalia; Graf, Monika; Hotfilder, Marc; Holdhof, Dörthe; Hartmann, Wolfgang; Bruns, Ann-Katrin; Brentrup, Angela; Liesche-Starnecker, Friederike; Maerkl, Bruno; Sandmann, Sarah; Varghese, Julian; Dugas, Martin; Pinto, Pedro H.; Balbach, Sebastian T.;Lu, I-Na; Rossig, Claudia; Soehnlein, Oliver; Canak, Aysegül; Ebinger, Martin; Schuhmann, Martin; Schittenhelm, Jens; Frühwald, Michael F.; Schüller, Ulrich; Albert, Thomas K.; Walter, Carolin; Bruder, Jan M.; Kerl, Kornelius. (2025) In: Nature Communications, 16, 5394. Research article (journal)
MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas Sigaud R.; Albert T.K.; Hess C.; Hielscher T.; Winkler N.; Kocher D.; Walter C.; Münter D.; Selt F.; Usta D.; Ecker J.; Brentrup A.; Hasselblatt M.; Thomas C.; Varghese J.; Capper D.; Thomale U.W.; Hernáiz Driever P.; Simon M.; Horn S.; Herz N.A.; Koch A.; Sahm F.; Hamelmann S.; Faria-Andrade A.; Jabado N.; Schuhmann M.U.; Schouten-van Meeteren A.Y.N.; Hoving E.; Brummer T.; van Tilburg C.M.; Pfister S.M.; Witt O.; Jones D.T.W.; Kerl K.; Milde T. (2023) In: Nature Communications, 14(1). Research article (journal)
Mitochondrial DNA mutations in Medulloblastoma Funke V.L.E.; Sandmann S.; Melcher V.; Seggewiss J.; Horvath J.; Jäger N.; Kool M.; Jones D.T.W.; Pfister S.M.; Milde T.; Rutkowski S.; Mynarek M.; Varghese J.; Sträter R.; Rust S.; Seelhöfer A.; Reunert J.; Fiedler B.; Schüller U.; Marquardt T.; Kerl K. (2023) In: Acta neuropathologica communications, 11(1). Research article (journal)
A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice Brugmans A.K.; Walter C.; Moreno N.; Göbel C.; Holdhof D.; de Faria F.W.; Hotfilder M.; Jeising D.; Frühwald M.C.; Skryabin B.V.; Rozhdestvensky T.S.; Wachsmuth L.; Faber C.; Dugas M.; Varghese J.; Schüller U.; Albert T.K.; Kerl K. (2023) In: Cellular and Molecular Neurobiology, 43(7). Research article (journal)
DRUG-CLASS SPECIFIC GENE-BASED MAPK SENSITIVITY SCORES (MSS) PREDICT SENSITIVITY TO MAPK INHIBITORS AND IDENTIFY IMMUNE INFILTRATION AS PUTATIVE TARGET IN PEDIATRIC LOW-GRADE GLIOMAS Sigaud, Romain; Albert, Thomas K.; Hess, Caroline; Hielscher, Thomas; Winkler, Nadine; Walter, Carolin; Muenter, Daniel; Selt, Florian; Usta, Diren; Ecker, Jonas; Brentrup, Angela; Hasselblatt, Martin; Thomas, Christian; Varghese, Julian; Capper, David; Thomale, Ulrich W.; Driever, Pablo Hernaiz; Simon, Michele; Horn, Svea; Herz, Nina Annika; Koch, Arend; Sahm, Felix; Mann, Stefan Hamel; Andrade, Augusto Faria; Jabado, Nada; Schouten-van Meeteren, Antoinette Y. N.; Hoving, Eelco; Brummer, Tilman; van Tilburg, Cornelis M.; Pfister, Stefan M.; Witt, Olaf; Jones, David T. W.; Kerl, Kornelius; Milde, Till (2023) In: Neuro-Oncology, 25. Research article (journal)

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Projects

CRC 1748: Principles of Reproduction – Unravelling the Molecular Mechanisms of Male Infertility Duration: 01/04/2026 - 31/12/2029 \| 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster
CRC 1748 - A01: Epigenetic mechanisms in the physiological development and malignant transformation of primordial germ cells Duration: 01/04/2026 - 31/12/2029 \| 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
Reproduction – from Genes to Molecules and Function Duration: 23/05/2022 - 31/12/2024 \| 2nd Funding period Funded by: Uni Münster-internal funding - Topical Programmes Type of project: Internally at the University of Münster funded project
Dauer- und Rezidivtherapie von Kindern mit Rhabdoiden Tumoren Duration: 01/02/2013 - 31/01/2016 Funded by: Horizont Kinderkrebshilfe Weseke e.V. Type of project: Individual project
Etablierung von Tumormarkern für Rhabdoidtumore des Gehirns Duration: 01/06/2012 - 30/06/2014 Funded by: Sonja Wasowicz Stiftung zur Förderung der medizinischen Forschung Type of project: Individual project

Prizes

Hermann-Seippel-Preis – Deutscher Forschungspreis für Kinderheilkunde
Awarded by: Stiftung Universitätsmedizin Essen
Award given to: Kerl, Kornelius
Date of awarding: 15/10/2016
Type of distinction: Research award or other distinction