Apl.-Prof. Dr. rer. nat. Thomas Budde

Current affiliations

Institute of Physiology I (Neurophysiology)

Publications

MMF induces antioxidative and anaplerotic pathways and is neuroprotective in hyperexcitability in vitro Gola, L; Bierhansl, L; Hummel, N; Korn, L; Pawlowski, M; Cerina, M; Hundehege, P; Budde, T; König, S; Meuth, S; Wiendl, H; Kovac, S (2023) In: Free Radical Biology and Medicine, 194 Type of Publication: Research article (journal)
A novel NMDA receptor test model based on hiPSC-derived neural cells Disse P, Aymanns I, Ritter N, Peischard S, Korn L, Wiendl H, Pawlowski M, Kovac S, Meuth SG, Budde T, Strutz-Seebohm N, Wünsch B, Seebohm G (2023) In: Biological Chemistry, Ahead of Print Type of Publication: Research article (journal)
Imaging of KCa3.1 Channels in Tumor Cells with PET and Small-Molecule Fluorescent Probes Thale, I.; Maskri, S.; Grey, L.; Todesca, L. M.; Budde, T.; Maisuls, I.; Strassert; C. A.; Koch, O.; Schwab, A.; Wünsch, B. (2023) In: ChemMedChem, 18(2) Type of Publication: Research article (journal)
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination. Kapell H; Fazio L; Dyckow J; Schwarz S; Cruz-Herranz A; Mayer C; Campos J; D Este E; Möbius W; Cordano C; Pröbstel AK; Gharagozloo M; Zulji A; Narayanan Naik V; Delank AK; Müntefering T; Cerina M; Sonner JK; Lerma-Martin C; Disse P; Sin JH; Sabeur K; Rychlik N; Srivastava R; Chavali M; Fitzgerald KC; Heidenreich M; Stadelmann C; Seebohm G; Platten M; Hemmer B; Budde T; Nave KA; Jentsch TJ; Engelhardt M; Green AJ; Acuna C; Calabresi PA; Friese MA; Schirmer L; Rowitch DH; Meuth SG (2023) In: Journal of Clinical Investigation, Ahead of Print Type of Publication: Research article (journal)
Validation of TREK1 ion channel activators as an immunomodulatory and neuroprotective strategy in neuroinflammation. Schroeter CB; Nelke C; Schewe M; Spohler L; Herrmann AM; Müntefering T; Huntemann N; Kuzikov M; Gribbon P; Albrecht S; Bock S; Hundehege P; Neelsen LC; Baukrowitz T; Seebohm G; Bittner S; Wünsch B; Budde T; Ruck T; Meuth SG (2023) In: Biological Chemistry, Ahead of Print Type of Publication: Research article (journal)

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Projects

RTG 2515: Chemical Biology of Ion Channels (Chembion) Duration: 01/04/2024 - 30/09/2028 \| 2nd Funding period Funded by: DFG - Research Training Group Type of project: Main DFG-project hosted at University of Münster
CRC TRR 128 B06: The role of the kallikrein-kinin system to functional and structural impairment of network activity in multiple sclerosis Duration: 01/01/2021 - 30/06/2024 \| 3rd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
RTG 2515: Chemical Biology of Ion Channels (Chembion) Duration: 01/10/2019 - 31/03/2024 \| 1st Funding period Funded by: DFG - Research Training Group Type of project: Main DFG-project hosted at University of Münster
Altered functions of ion channels, membrane receptors and neuronal networks associated with thalamocortical dysrhythmia syndrome Duration: 01/03/2018 - 28/02/2021 Funded by: DFG - Individual Grants Programme Type of project: Individual project
Optogenetic control of epileptic seizures by means of simultaneous calcium measurement and in a fMRI mapped network Duration: 01/10/2016 - 30/09/2019 Funded by: DFG - Individual Grants Programme Type of project: Individual project

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Prizes

PHOENIX Pharmazie Wissenschaftspreis 2020
Awarded by: PHOENIX group
Award given to: Schreiber, Julian A.; Schepmann, Dirk; Frehland, Bastian; Thum, Simone; Datunashvili, Maia; Budde, Thomas; Hollmann, Michael; Strutz-Seebohm, Nathalie; Wünsch, Bernhard; Seebohm, Guiscard
Announced at: 10/12/2020 | Date of awarding: 15/12/2020
Type of distinction: Best publication award

Doctorates

Synaptic connectivity within the hippocampal-neocortical structure and the effect of long-term potentiation Candidate: Kathirgamachandrakumar, Nirogi \| Supervisors: Gorji, Ali; Budde, Thomas \| Reviewers: Gorji, Ali; Budde, Thomas Period of time: 01/01/2020 - 18/01/2023 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Die Funktion von 2-Porendomänen K+-Kanälen in Neuronen des Nucleus reticularis thalami Candidate: Krauth, Valerie \| Supervisors: Budde, Thomas; Wünsch Bernhard \| Reviewers: Budde, Thomas; Wünsch Bernhard Period of time: 01/09/2019 - 01/10/2022 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Pharmacological and immunological modulation of KCNQ potassium channels in inflammatory demyelination Candidate: Facio, Luca \| Supervisors: Budde, Thomas; Wünsch, Bernhard \| Reviewers: Budde, Thomas; Wünsch, Bernhard Period of time: 01/11/2017 - 04/05/2022 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Analyse von Schrittmacherströmen in HCN4-defizienten Mäusen Candidate: Rottmann, Matthias \| Supervisors: Budde, Thomas; Seebohm, Guiscard \| Reviewers: Budde, Thomas; Seebohm, Guiscard Period of time: 01/01/2020 - 27/01/2022 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
The impact of cyclic dinucleotides on innate immune recognition and control of adaptive immune responses Candidate: Masanneck, Lars \| Supervisors: Meuth, Sven; Budde, Thomas \| Reviewers: Meuth, Sven; Budde, Thomas; Seebohm, Guiscard; Scheutzel, Petra Period of time: 01/11/2019 - 25/11/2021 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

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RTG 2515: Chemical Biology of Ion Channels (Chembion) Duration: 01/04/2024 - 30/09/2028 \| 2nd Funding period Funded by: DFG - Research Training Group Type of project: Main DFG-project hosted at University of Münster
CRC TRR 128 B06: The role of the kallikrein-kinin system to functional and structural impairment of network activity in multiple sclerosis Duration: 01/01/2021 - 30/06/2024 \| 3rd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster
RTG 2515: Chemical Biology of Ion Channels (Chembion) Duration: 01/10/2019 - 31/03/2024 \| 1st Funding period Funded by: DFG - Research Training Group Type of project: Main DFG-project hosted at University of Münster
Altered functions of ion channels, membrane receptors and neuronal networks associated with thalamocortical dysrhythmia syndrome Duration: 01/03/2018 - 28/02/2021 Funded by: DFG - Individual Grants Programme Type of project: Individual project
Optogenetic control of epileptic seizures by means of simultaneous calcium measurement and in a fMRI mapped network Duration: 01/10/2016 - 30/09/2019 Funded by: DFG - Individual Grants Programme Type of project: Individual project

Synaptic connectivity within the hippocampal-neocortical structure and the effect of long-term potentiation Candidate: Kathirgamachandrakumar, Nirogi \| Supervisors: Gorji, Ali; Budde, Thomas \| Reviewers: Gorji, Ali; Budde, Thomas Period of time: 01/01/2020 - 18/01/2023 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Die Funktion von 2-Porendomänen K+-Kanälen in Neuronen des Nucleus reticularis thalami Candidate: Krauth, Valerie \| Supervisors: Budde, Thomas; Wünsch Bernhard \| Reviewers: Budde, Thomas; Wünsch Bernhard Period of time: 01/09/2019 - 01/10/2022 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Pharmacological and immunological modulation of KCNQ potassium channels in inflammatory demyelination Candidate: Facio, Luca \| Supervisors: Budde, Thomas; Wünsch, Bernhard \| Reviewers: Budde, Thomas; Wünsch, Bernhard Period of time: 01/11/2017 - 04/05/2022 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Analyse von Schrittmacherströmen in HCN4-defizienten Mäusen Candidate: Rottmann, Matthias \| Supervisors: Budde, Thomas; Seebohm, Guiscard \| Reviewers: Budde, Thomas; Seebohm, Guiscard Period of time: 01/01/2020 - 27/01/2022 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
The impact of cyclic dinucleotides on innate immune recognition and control of adaptive immune responses Candidate: Masanneck, Lars \| Supervisors: Meuth, Sven; Budde, Thomas \| Reviewers: Meuth, Sven; Budde, Thomas; Seebohm, Guiscard; Scheutzel, Petra Period of time: 01/11/2019 - 25/11/2021 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster