Professur für Biochemie (Prof. Klempnauer)

Status: Organisation is ended

Address:

Wilhelm-Klemm-Straße 2

48149 Münster

Germany

Publications

Natural Products with Antitumor Potential targeting the MYB-C/EBPbeta-p300 Transcription Module Schmidt TJ, Klempnauer K-H. (2022) In: Molecules, 27. doi:10.3390/molecules27072077 Research article (journal) \| Peer reviewed \| Published
PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs Haas A, Nilges BS, Leidel SA, Klempnauer K-H (2020) In: Scientific Reports, 2020. Research article (journal) \| Peer reviewed \| Published
Activation of the oncogenic transcription factor B-Myb via multisite phosphorylation and prolyl cis/trans isomerization. Werwein E, Cibis H, Hess D, Klempnauer KH (2019) In: Nucleic Acids Research, 47. Research article (journal) \| Peer reviewed \| Published
A novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity. Yusenko M, Jakobs A, Klempnauer KH (2018) In: Scientific Reports, 8. Research article (journal) \| Peer reviewed \| Published
1. The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression. Coulibaly A, Haas A, Steinmann S, Jakobs A, Schmidt TJ, Klempnauer KH. (2018) In: PloS one, 13. Research article (journal) \| Peer reviewed \| Published

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Projects

Charakterisierung niedermolekularer Inhibitoren des Transkriptionsfaktors MYB Duration: 01/10/2020 - 30/09/2021 Funded by: Wilhelm Sander-Stiftung Type of project: Individual project
Development of small molecule inhibitors of the transcription factor C/EBPß Duration: 01/01/2019 - 31/12/2020 Funded by: José Carreras Leukämie-Stiftung Type of project: Individual project
Untersuchungen zum anti-leukämischen Potential niedermolekularer Inhibitoren C/EBPß Duration: 01/03/2018 - 29/02/2020 Funded by: Deutsche Krebshilfe e.V. Type of project: Individual project
Untersuchungen zur Funktion des Transkriptionsfaktors B-Myb in der G2/M-Phase des Zellzyklus Duration: 01/07/2017 - 30/06/2019 Funded by: Wilhelm Sander-Stiftung Type of project: Individual project
Inhibition of transcription factor c-Myb with small-molecule inhibitors Duration: 01/01/2017 - 31/12/2019 Funded by: Else Kröner-Fresenius-Foundation Type of project: Individual project

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Promotionen

Complex Regulation of Secondary Metabolism in the Phytopathogenic Fungus Fusarium fujikuroi Candidate: Dr. Rösler, Sarah M. \| Supervisors: Prof. Dr. Humpf, Hans-Ulrich Prof. Dr. Tudzynski, Bettina Period of time: 01/01/2013 - 31/07/2016 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Natural products as Inhibitors of c-Myb-dependent Transcription Processes (Thesis written in German) Candidate: Schomburg, Caroline \| Supervisors: Schmidt, Thomas J.; Klempnauer, Karl-Heinz \| Reviewers: Schmidt, Thomas J.; Klempnauer, Karl-Heinz Period of time: 01/11/2009 - 09/04/2013 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Identifikation und Charakterisierung der nukleären Funktion und DNA-Interaktion von RGS2 in myeloischen Zellen Candidate: Rehage, Maike \| Supervisors: Klempnauer, Karl-Heinz Period of time: until 21/10/2011 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
B-Myb in der zellulären Antwort auf DNA-Schäden Candidate: Džuganova, Monika \| Supervisors: Klempnauer, Karl-Heinz Period of time: until 07/06/2011 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Untersuchungen zur Translationsregulation durch den Tumorsuppressor Pdcd4 und Identifizierung einer spezifisch regulierten mRNA Candidate: Wedeken, Lena \| Supervisors: Klempnauer, Karl-Heinz Period of time: until 03/05/2011 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

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Parent organisational units

University of Münster
- Schools and Faculties
  - FB12 - Faculty of Chemistry and Pharmacy
    - Institute of Biochemistry