Institute of Pharmacology and Toxicology

Status: Organisation is active

Website: https://www.medizin.uni-muenster.de/pharmtox/

Address:

Domagkstraße 12

48149 Münster

Germany

Publications

Impaired myocellular Ca2+ cycling in protein phosphatase PP2A-B56α KO mice is normalized by β-adrenergic stimulation Glaser D, Heinick A, Herting JR, Massing F, Müller FU, Pauls P, Rozhdestvensky TS, Schulte JS, Seidl MD, Skryabin BV, Stümpel F, Kirchhefer U. (2022) In: Journal of Biological Chemistry, 298(9). doi:10.1016/j.jbc.2022.102362 Research article (journal) \| Peer reviewed \| Published
Libanon : im Zwischenland Kirchhefer Anna, Kirchhefer Uwe (2021) Berlin: MANA-Verlag. Book (monograph) \| Published
A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart Horsthemke M, Nutter LMJ, Bachg AC, Skryabin BV, Honnert U, Zobel T, Bogdan S, Stoll M, Seidl MD, Mueller FU, Ravens U, Unger A, Linke WA, Gorp PRR, Vries AAF, Bahler M, Hanley PJ (2019) In: Journal of Biological Chemistry, 2019(294), 7202-7218. doi:10.1074/jbc.RA118.004560 Research article (journal) \| Peer reviewed \| Published
Progressive impairment of atrial myocyte function during left ventricular hypertrophy and heart failure Pluteanu F, Nikonova Y, Holzapfel A, Herzog B, Scherer A, Preisenberger J, Plačkić J, Scheer K, Ivanova T, Bukowska A, Goette A, Kockskämper J (2018) In: Journal of Molecular and Cellular Cardiology, 114, 253-263. doi:10.1016/j.yjmcc.2017.11.020 Research article (journal) \| Peer reviewed \| Published
Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes Krysiak J, Unger A, Beckendorf L, Hamdani N, Frieling-Salewsky M, Redfield MM, {Dos Remedios} CG, Sheikh F, Gergs U, Boknik P, Linke WA (2018) In: Nature Communications, 9(1). doi:10.1038/s41467-017-02483-3 Research article (journal) \| Peer reviewed \| Published

Show all publications (228)

Projects

Hemmung der Adenylylcyclase 5 durch Annexin A4 und deren Bedeutung für das kardiale Remodeling Duration: 01/01/2017 - 31/12/2019 Type of project: Own resources project
Bedeutung der Induktion von ICER und smICER im Herzen Duration: 15/02/2016 - 14/02/2019 \| 3rd Funding period Funded by: DFG - Individual Grants Programme Type of project: Individual project
Relevanz eines neu identifizierten induzierbaren intronischen Promotors im Crem-Gen Duration: 01/04/2011 - 31/12/2014 Funded by: DFG - Individual Grants Programme Type of project: Individual project
The European Network for Translational Research in Atrial Fibrillation (EUTRAF) Duration: 01/11/2010 - 31/10/2015 Funded by: EC FP 7 - Large-scale integrating project Type of project: EU-project hosted outside University of Münster
Bedeutung cAMP-abhängiger Transkriptionsfaktoren bei der Herzinsuffizienz Duration: 01/02/2007 - 31/01/2010 \| 3rd Funding period Funded by: DFG - Individual Grants Programme Type of project: Individual project

Show all projects (9)

Preisverleihungen

Ehrendoktorwürde
Awarded by: Comenius University in Bratislava
Award given to: Schmitz, Wilhelm
Announced at: 15/09/2012 | Date of awarding: 15/09/2012
Type of distinction: Research award or other distinction

Promotionen

Preclinical evaluation of combined topoisomerase and proteasome inhibition against pediatric malignancies Candidate: Destanovic, Edvin \| Supervisors: Boos, Joachim; Boknik, Peter; Lanvers-Kaminsky, Claudia Period of time: until 23/09/2019 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Die Bedeutung des cAMP-abhängigen Transkriptionsfaktors CREM-IbC-X für herzinsuffizienzbedingte ventrikuläre Arrhythmien Candidate: Fehrmann, Edda \| Supervisors: Wünsch, Bernhard Period of time: until 29/05/2018 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Vergleich zweier Messmethoden der Aktivität pegylierter E. coli Asparaginase im Rahmen der internationalen multizentrischen Studie AIEOP-BFM ALL 2009 Candidate: Rüffer, Andrea \| Supervisors: Boos, Joachim; Boknik, Peter; Lanvers-Kaminsky, Claudia Period of time: until 16/10/2017 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Die Bedeutung der Histondeacetylase-Inhibition für die Pathophysiologie des Vorhofflimmerns Candidate: Scholz, Beatrix \| Supervisors: Wünsch, Bernhard Period of time: 01/04/2011 - 30/09/2017 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Bedeutung von Annexin A4 für die Physiologie des Herzens Candidate: Husser, Xenia \| Supervisors: Liebau, Eva; Müller, Frank Ulrich Period of time: until 12/02/2016 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

Show all doctorates (17)

Parent organisational units

University of Münster
- Schools and Faculties
  - FB05 - Faculty of Medicine
    - Center of Clinical-Theoretical Medicine II

Impaired myocellular Ca2+ cycling in protein phosphatase PP2A-B56α KO mice is normalized by β-adrenergic stimulation Glaser D, Heinick A, Herting JR, Massing F, Müller FU, Pauls P, Rozhdestvensky TS, Schulte JS, Seidl MD, Skryabin BV, Stümpel F, Kirchhefer U. (2022) In: Journal of Biological Chemistry, 298(9). doi:10.1016/j.jbc.2022.102362 Research article (journal) \| Peer reviewed \| Published
Libanon : im Zwischenland Kirchhefer Anna, Kirchhefer Uwe (2021) Berlin: MANA-Verlag. Book (monograph) \| Published
A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart Horsthemke M, Nutter LMJ, Bachg AC, Skryabin BV, Honnert U, Zobel T, Bogdan S, Stoll M, Seidl MD, Mueller FU, Ravens U, Unger A, Linke WA, Gorp PRR, Vries AAF, Bahler M, Hanley PJ (2019) In: Journal of Biological Chemistry, 2019(294), 7202-7218. doi:10.1074/jbc.RA118.004560 Research article (journal) \| Peer reviewed \| Published
Progressive impairment of atrial myocyte function during left ventricular hypertrophy and heart failure Pluteanu F, Nikonova Y, Holzapfel A, Herzog B, Scherer A, Preisenberger J, Plačkić J, Scheer K, Ivanova T, Bukowska A, Goette A, Kockskämper J (2018) In: Journal of Molecular and Cellular Cardiology, 114, 253-263. doi:10.1016/j.yjmcc.2017.11.020 Research article (journal) \| Peer reviewed \| Published
Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes Krysiak J, Unger A, Beckendorf L, Hamdani N, Frieling-Salewsky M, Redfield MM, {Dos Remedios} CG, Sheikh F, Gergs U, Boknik P, Linke WA (2018) In: Nature Communications, 9(1). doi:10.1038/s41467-017-02483-3 Research article (journal) \| Peer reviewed \| Published

Preclinical evaluation of combined topoisomerase and proteasome inhibition against pediatric malignancies Candidate: Destanovic, Edvin \| Supervisors: Boos, Joachim; Boknik, Peter; Lanvers-Kaminsky, Claudia Period of time: until 23/09/2019 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Die Bedeutung des cAMP-abhängigen Transkriptionsfaktors CREM-IbC-X für herzinsuffizienzbedingte ventrikuläre Arrhythmien Candidate: Fehrmann, Edda \| Supervisors: Wünsch, Bernhard Period of time: until 29/05/2018 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Vergleich zweier Messmethoden der Aktivität pegylierter E. coli Asparaginase im Rahmen der internationalen multizentrischen Studie AIEOP-BFM ALL 2009 Candidate: Rüffer, Andrea \| Supervisors: Boos, Joachim; Boknik, Peter; Lanvers-Kaminsky, Claudia Period of time: until 16/10/2017 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Die Bedeutung der Histondeacetylase-Inhibition für die Pathophysiologie des Vorhofflimmerns Candidate: Scholz, Beatrix \| Supervisors: Wünsch, Bernhard Period of time: 01/04/2011 - 30/09/2017 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Bedeutung von Annexin A4 für die Physiologie des Herzens Candidate: Husser, Xenia \| Supervisors: Liebau, Eva; Müller, Frank Ulrich Period of time: until 12/02/2016 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster