University of Münster
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Syndecan-1 and heparanase as novel regulators of colon cancer stem cell function

Basic data of the doctoral examination procedure

Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Period of time: 01/09/2011 - 01/04/2015
Status: completed
Candidate: Kumar Katakam, Sampath
Doctoral subject: Biologie
Doctoral degree: Dr. rer. nat.
Awarded by: Department 13 - Biology
Supervisors: Götte, Martin; Moerschbacher, Bruno; Greve, Burkhard

Supervision at the University of Münster

Götte, Martin
Department of Gynecology and Obstetrics
Greve, Burkhard
Clinic for Radiotherapy
Moerschbacher, Bruno
Molecular Phytopathology and Renewable Resources - Group Prof. Bruno Moerschbacher

Projects in which the doctoral examination procedure takes/took place

IRTG 1549 - Molecular and Cellular Glyco-Sciences (MCGS). Understanding Structure/Function Relationships of Carbohydrate/Protein-Interactions (MCGS)
Duration: 10/03/2009 - 31/03/2014 | 1st Funding period
Funded by: DFG - International Research Training Group
Type of project: Main DFG-project hosted at University of Münster

Publications resulting from doctoral examination procedure

The heparan sulfate proteoglycan syndecan-1 regulates colon cancer stem cell function via a focal adhesion kinase-Wnt signaling axis
Kumar Katakam S, Tria V, Sim WC, Yip GW, Molgora S, Karnavas T, Elghonaimy EA, Pelucchi P, Piscitelli E, Ibrahim SA, Zucchi I, Reinbold R, Greve B, Götte M. (2020)
In: The FEBS Journal, 2020. doi:10.1111/febs.15356
Research article (journal) | Peer reviewed | online first
Syndecan-1-Dependent Regulation of Heparanase Affects Invasiveness, Stem Cell Properties, and Therapeutic Resistance of Caco2 Colon Cancer Cells
Katakam SK, Pelucchi P, Cocola C, Reinbold R, Vlodavsky I, Greve B, Götte M. (2020)
In: Frontiers in Oncology, 10. doi:10.3389/fonc.2020.00774
Research article (journal) | Peer reviewed | Published
The Heparan Sulfate Sulfotransferases HS2ST1 and HS3ST2 Are Novel Regulators of Breast Cancer Stem-Cell Properties
Teixeira FCOB, Vijaya Kumar A, Kumar Katakam S, Cocola C, Pelucchi P, Graf M, Kiesel L, Reinbold R, Pavao MSG, Greve B, Götte M (2020)
In: Frontiers in cell and developmental biology, 8. doi:10.3389/fcell.2020.559554
Research article (journal) | Peer reviewed | Published
Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance
Vitale D, Kumar Katakam S, Greve B, Jang B, Oh ES, Alaniz L, Götte M. (2019)
In: The FEBS Journal, 286(15), 2870-2882. doi:10.1111/febs.14967
Research article (journal) | Peer reviewed | Published
Heparan sulphate as a regulator of leukocyte recruitment in inflammation
Kumar A., Katakam S., Urbanowitz A., Götte M. (2015)
In: Current Protein and Peptide Science, 16(1), 77-86.
Research article (journal) | Peer reviewed | Published