Syndecan-1 and heparanase as novel regulators of colon cancer stem cell function

Basic data of the doctoral examination procedure

Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

Period of time: 01/09/2011 - 01/04/2015

Status: completed

Candidate: Kumar Katakam, Sampath

Doctoral subject: Biologie

Doctoral degree: Dr. rer. nat.

Awarded by: Department 13 - Biology

Supervisors: Götte, Martin; Moerschbacher, Bruno; Greve, Burkhard

Götte, Martin	Department of Gynecology and Obstetrics
Greve, Burkhard	Clinic for Radiotherapy
Moerschbacher, Bruno	Molecular Phytopathology and Renewable Resources - Group Prof. Bruno Moerschbacher

Duration: 10/03/2009 - 31/03/2014 | 1st Funding period

Funded by: DFG - International Research Training Group

Type of project: Main DFG-project hosted at University of Münster

The heparan sulfate proteoglycan syndecan-1 regulates colon cancer stem cell function via a focal adhesion kinase-Wnt signaling axis Kumar Katakam S, Tria V, Sim WC, Yip GW, Molgora S, Karnavas T, Elghonaimy EA, Pelucchi P, Piscitelli E, Ibrahim SA, Zucchi I, Reinbold R, Greve B, Götte M. (2020) In: The FEBS Journal, 2020. Research article (journal)
Syndecan-1-Dependent Regulation of Heparanase Affects Invasiveness, Stem Cell Properties, and Therapeutic Resistance of Caco2 Colon Cancer Cells Katakam SK, Pelucchi P, Cocola C, Reinbold R, Vlodavsky I, Greve B, Götte M. (2020) In: Frontiers in Oncology, 10. Research article (journal)
The Heparan Sulfate Sulfotransferases HS2ST1 and HS3ST2 Are Novel Regulators of Breast Cancer Stem-Cell Properties Teixeira FCOB, Vijaya Kumar A, Kumar Katakam S, Cocola C, Pelucchi P, Graf M, Kiesel L, Reinbold R, Pavao MSG, Greve B, Götte M (2020) In: Frontiers in cell and developmental biology, 8. Research article (journal)
Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance Vitale D, Kumar Katakam S, Greve B, Jang B, Oh ES, Alaniz L, Götte M. (2019) In: The FEBS Journal, 286(15). Research article (journal)
Heparan sulphate as a regulator of leukocyte recruitment in inflammation Kumar A., Katakam S., Urbanowitz A., Götte M. (2015) In: Current Protein and Peptide Science, 16(1). Research article (journal)