The role of heparan sulfate 3-O- and 2-O-sulfation in breast cancer pathogenesis

Basic data of the doctoral examination procedure

Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

Period of time: 01/04/2011 - 01/07/2014

Status: completed

Candidate: Vijaya Kumar, Archana

Doctoral subject: Biologie

Doctoral degree: Dr. rer. nat.

Awarded by: Department 13 - Biology

Supervisors: Götte, Martin; Moerschbacher, Bruno

Supervision at the University of Münster

Götte, Martin	Department of Gynecology and Obstetrics
Moerschbacher, Bruno	Molecular Phytopathology and Renewable Resources - Group Prof. Bruno Moerschbacher

Projects in which the doctoral examination procedure takes/took place

IRTG 1549 - Molecular and Cellular Glyco-Sciences (MCGS). Understanding Structure/Function Relationships of Carbohydrate/Protein-Interactions (MCGS)

Duration: 10/03/2009 - 31/03/2014 | 1st Funding period

Funded by: DFG - International Research Training Group

Type of project: Main DFG-project hosted at University of Münster

Publications resulting from doctoral examination procedure

HS2ST1-dependent signaling pathways determine breast cancer cell viability, matrix interactions, and invasive behavior Vijaya Kumar A, Brézillon S, Untereiner V, Sockalingum GD, Kumar Katakam S, Mohamed HT, Kemper B, Greve B, Mohr B, Ibrahim SA, Goycoolea FM, Kiesel L, Pavão MSG, Motta JM, Götte M. (2020) In: Cancer Science, 8(111), 2907-2922. doi:10.1111/cas.14539 Research article (journal) \| Peer reviewed \| Published
The Heparan Sulfate Sulfotransferases HS2ST1 and HS3ST2 Are Novel Regulators of Breast Cancer Stem-Cell Properties Teixeira FCOB, Vijaya Kumar A, Kumar Katakam S, Cocola C, Pelucchi P, Graf M, Kiesel L, Reinbold R, Pavao MSG, Greve B, Götte M (2020) In: Frontiers in cell and developmental biology, 8. doi:10.3389/fcell.2020.559554 Research article (journal) \| Peer reviewed \| Published
Heparan sulphate as a regulator of leukocyte recruitment in inflammation Kumar A., Katakam S., Urbanowitz A., Götte M. (2015) In: Current Protein and Peptide Science, 16(1), 77-86. Research article (journal) \| Peer reviewed \| Published
HS3ST2 modulates breast cancer cell invasiveness and chemosensitivity via MAP kinase- and TCF7L2/TCF4-dependent regulation of protease and cadherin expression Kumar A, Gassar E, Spillmann D, Hulsewig C, Kiesel L, Stock C, Yip G, Gotte M (2014) In: Oncology Research and Treatment, 37 1, 95-95. Research article (journal) \| Peer reviewed \| Published
HS3ST2 modulates breast cancer cell invasiveness via MAP kinase-and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression Kumar A., Gassar E., Spillmann D., Stock C., Sen Y., Zhang T., Van Kuppevelt T., Hulsewig C., Kozlowski E., Pavao M., Ibrahim S., Poeter M., Rescher U., Kiesel L., Koduru S., Yip G., Gotte M. (2014) In: International Journal of Cancer, 135(11), 2579-2592. doi:10.1002/ijc.28921 Research article (journal) \| Peer reviewed \| Published

Preisverleihungen erhalten für Promotion

ISGE-Nachwuchspreis/Kongressstipendium
Awarded by: Internationale Gesellschaft für Gynäkologische Endokrinologie (ISGE)
Award given to: Vijaya Kumar, Archana; Götte, Martin
Date of awarding: 15/03/2014
Type of distinction: Research award or other distinction

HS2ST1-dependent signaling pathways determine breast cancer cell viability, matrix interactions, and invasive behavior Vijaya Kumar A, Brézillon S, Untereiner V, Sockalingum GD, Kumar Katakam S, Mohamed HT, Kemper B, Greve B, Mohr B, Ibrahim SA, Goycoolea FM, Kiesel L, Pavão MSG, Motta JM, Götte M. (2020) In: Cancer Science, 8(111), 2907-2922. doi:10.1111/cas.14539 Research article (journal) \| Peer reviewed \| Published
The Heparan Sulfate Sulfotransferases HS2ST1 and HS3ST2 Are Novel Regulators of Breast Cancer Stem-Cell Properties Teixeira FCOB, Vijaya Kumar A, Kumar Katakam S, Cocola C, Pelucchi P, Graf M, Kiesel L, Reinbold R, Pavao MSG, Greve B, Götte M (2020) In: Frontiers in cell and developmental biology, 8. doi:10.3389/fcell.2020.559554 Research article (journal) \| Peer reviewed \| Published
Heparan sulphate as a regulator of leukocyte recruitment in inflammation Kumar A., Katakam S., Urbanowitz A., Götte M. (2015) In: Current Protein and Peptide Science, 16(1), 77-86. Research article (journal) \| Peer reviewed \| Published
HS3ST2 modulates breast cancer cell invasiveness and chemosensitivity via MAP kinase- and TCF7L2/TCF4-dependent regulation of protease and cadherin expression Kumar A, Gassar E, Spillmann D, Hulsewig C, Kiesel L, Stock C, Yip G, Gotte M (2014) In: Oncology Research and Treatment, 37 1, 95-95. Research article (journal) \| Peer reviewed \| Published
HS3ST2 modulates breast cancer cell invasiveness via MAP kinase-and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression Kumar A., Gassar E., Spillmann D., Stock C., Sen Y., Zhang T., Van Kuppevelt T., Hulsewig C., Kozlowski E., Pavao M., Ibrahim S., Poeter M., Rescher U., Kiesel L., Koduru S., Yip G., Gotte M. (2014) In: International Journal of Cancer, 135(11), 2579-2592. doi:10.1002/ijc.28921 Research article (journal) \| Peer reviewed \| Published