Mannose-enthaltende Nahrungsergänzungsmittel – wie sieht die Qualitätssituation aus? [Dietary Supplements with Mannose: What do we Know about Their Quality?]

Lechtenberg, Matthias; Quandt-Rusch, Bettina; Hensel, Andreas

Forschungsartikel (Zeitschrift) | Peer reviewed

Zusammenfassung

Uncomplicated urinary tract infections are among the most common infections and affect a large proportion of the population. In addition to antibiotic and/or phytotherapeutic treatment, D-mannose is also frequently used, this also with regard to possible recurrence prophylaxis. D-mannose interacts with a mannose-binding protein (FimH) of the fimbriae of uropathogenic E. coli and thus blocks the interaction and adhesion of the bacterium with the human host cell. Currently, there are no drug approvals for D-mannose. Preparations available on the market are assigned to the two product segments of food supplements or medical devices. Since in the course of various analytical tests food supplements can have relevant quality deficiencies, a representative cross-section investigation of D-mannose preparations available on the German market was investigated in the present study. The D-mannose content was analysed using a specific chromatographic method (HPLC-IEC-PAD). Fortunately, all test samples proved to be in compliance with the specifications.

Details zur Publikation

FachzeitschriftZeitschrift für Phytotherapie
Jahrgang / Bandnr. / Volume43
Ausgabe / Heftnr. / Issue5
Seitenbereich204-208
StatusVeröffentlicht
Veröffentlichungsjahr2022
DOI10.1055/a-1857-9517
Link zum Volltexthttps://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1857-9517
StichwörterD-Mannose - urinary tract infections - dietary supplement - quality

Autor*innen der Universität Münster

Hensel, Andreas
Institut für Pharmazeutische Biologie und Phytochemie
Lechtenberg, Matthias
Institut für Pharmazeutische Biologie und Phytochemie