Stereoselective interaction between DNA and chiral surfaces

Tang KJ, Gan H, Li Y, Chi LF, Sun TL, Fuchs H

Zusammenfassung

ssDNA exhibits much different adsorption behaviors on enantiomer modified surfaces, which can be explained by the stereoselective H-bond interaction between DNA and the chiral surfaces. This effect not only may help to understand the stereospecific cell/substrate interaction and the origin of the chiral preference in nature but also brings novel insights to the study of DNA properties and the application in biochemical devices.