Characterization of clonal relatedness among the natural population of Staphylococcus aureus strains by using spa sequence typing and the BURP (based upon repeat patterns) algorithm.
Mellmann A, Weniger T, Berssenbrügge C, Keckevoet U, Friedrich AW, Harmsen D, Grundmann H
Forschungsartikel (Zeitschrift)Zusammenfassung
We evaluated the BURP (based upon repeat patterns) algorithm, which relies on sequencing of the Staphylococcus aureus protein A gene (spa), for its ability to infer clonal relatedness within a population of 110 wild-type strains. BURP clustering of the resulting 66 spa types was highly concordant with multilocus sequence typing (96.5% concordance) and pulsed-field gel electrophoresis (94.9%).
Details zur Publikation
Fachzeitschrift: Journal of Clinical Microbiology (J Clin Microbiol)
Jahrgang / Bandnr. / Volume: 46
Ausgabe / Heftnr. / Issue: 8
Seitenbereich: 2805-2808
Status: Veröffentlicht
Veröffentlichungsjahr: 2008
Sprache, in der die Publikation verfasst ist: Englisch
DOI: 10.1128/JCM.00071-08
Stichwörter: Humans; DNA Bacterial; Sequence Analysis DNA. Staphylococcus aureus; Cluster Analysis; Staphylococcal Protein A. Bacterial Typing Techniques; Electrophoresis Gel Pulsed-Field; Genotype; Humans; DNA Bacterial; Sequence Analysis DNA. Staphylococcus aureus; Cluster Analysis; Staphylococcal Protein A. Bacterial Typing Techniques; Electrophoresis Gel Pulsed-Field; Genotype
Autor*innen der Universität Münster
| Berssenbrügge, Christoph | Medizinische Klinik B (Med B) |
| Harmsen, Dag | Poliklinik für Parodontologie und Zahnerhaltung |
| Mellmann, Alexander | Institut für Hygiene |