Observational approach (pilot project): “Lift Yourself” program – safe physical exercise in Fabry Disease (Fabry and Sport)

Grunddaten zu diesem Projekt

Beschreibung

Physical inactivity is an established risk factor for cardiovascular disease, especially in the background of chronic diseases such as type 2 diabetes mellitus, essential hypertension, cancer, and also FD. On the other hand, physical exercise is a key component in primary and secondary prevention of cardiovascular disease. As FD is a multisystemic disorder with cardiovascular, renal and neurologic manifestations, and FD mortality is mostly due to cardiovascular disease manifestations, physical exercise may become a therapy cornerstone as it mayPhysical exercise in Fabry Disease – “Lift Yourself” program; 2 Univ.-Prof. Dr. Dr. S-M. Brand, 01.08.2013improve FD patients’ daily fitness, overall wellbeing, and cardiovascular morbidity and mortality.“Lift Yourself” is a health and wellbeing program developed by the Directorate of Sport, Exercise and Physiotherapy at the University of Salford in the United Kingdom (supported by Shire), but until now has not been clinically monitored and implemented in Fabry centers.The Institute of Sports Medicine at the University Hospital Muenster has a well-organized infrastructure with all facilities to implement the program in cooperation with the interdisciplinary Fabry-Center in Muenster, that takes care of approximately 155 FD patients (~50-60% females) by nephrologists, cardiologists, and neurologists yearly.The current pilot project represents an observational approach to implement the “Lift Yourself” program as a safe physical exercise approach in patients with Morbus Fabry. It is envisaged to follow-up 10 - 15 well-characterized, clinically stable Fabry patients from the Interdisciplinary Fabry-Center of Münster (IFAZ) with a physical training according to the “Lift Yourself” program.