Andexanet-Alfa-Associated Heparin Resistance in the Context of Hemorrhagic Stroke.

Müther M, Schwindt W, Mesters RM, Minnerup J, Stracke P, Holling M, Wiendl H, Stummer W

Abstract

Although well known to hematologists, the phenomenon is underrecognized among stroke clinicians. However, patients with intracranial hemorrhage frequently undergo endovascular or surgical interventions that require periprocedural administration of heparin.