Knockdown of the stem cell marker Musashi-1 inhibits endometrial cancer growth and sensitizes cells to radiation.

Falke I, Troschel FM, Palenta H, Löblein MT, Brüggemann K, Borrmann K, Eich HT, Götte M, Greve B

Research article (journal) | Peer reviewed

Abstract

Musashi-1 knockdown resulted in a strong decrease in endometrial cancer proliferation and a loss of radioresistance, suggesting therapeutic potential.

Details about the publication

JournalStem Cell Research and Therapy (Stem Cell Res Ther)
Volume13
Issue1
Page range212-212
StatusPublished
Release year2022 (26/06/2022)
Language in which the publication is writtenEnglish
DOI10.1186/s13287-022-02891-3
KeywordsAnimals; Biomarkers; Blotting, Western; Cell Proliferation; Endometrial Neoplasms; Female; Humans; Mice; Stem Cells

Authors from the University of Münster

Troschel, Fabian Martin
Clinic for Radiotherapy