Phenol-benzoxazolone bioisosteres of GluN2B-NMDA receptor antagonists: unexpected rearrangement during reductive alkylation with phenylcyclohexa-none.

A. Markus, J. A. Schreiber, G. Goerges, B. Frehland, D. Schepmann, C. Daniliuc, R. Fröhlich, G. Seebohm, B. Wünsch

Research article (journal) | Peer reviewed

Details about the publication

JournalArchiv der Pharmazie / Chemistry in Life Sciences (ArchPharm)
Volume2022
Article numbere2200225
StatusPublished
Release year2022
Language in which the publication is writtenEnglish
DOI10.1002/ardp.202200225
Keywordsbenzoxazolone bioisosteres; GluN2B subunit‐ containing NMDA receptor; negative allosteric modulators; rearrangement; X‐ray crystal structure

Authors from the University of Münster

Goerges, Gunnar Marten
Institut für Genetik von Herzerkrankungen (IfGH)
Wünsch, Bernhard
Professur für Pharmazeutische Chemie (Prof. Wünsch)