Detecting myositis as a cause of unexplained dysphagia: Proposal for a diagnostic algorithm.
Labeit, Bendix; Grond, Thalia; Beule, Achim G; Boehmer, Maik; Thomas, Christian; Muhle, Paul; Claus, Inga; Roderigo, Malte, Rudack, Claudia; Wiendl, Heinz; Dziewas, Rainer; Warnecke, Tobias; Suntrup-Krueger, Sonja
Research article (journal) | Peer reviewedAbstract
Over a period of 4 years, patients with unexplained dysphagia were offered diagnostic evaluation according to a specific algorithm: The pattern of dysphagia was characterized by instrumental assessment (swallowing endoscopy, videofluoroscopy, high-resolution manometry). Patients with an IIM-compatible dysphagia pattern were subjected to further IIM-focused diagnostic procedures, including whole-body muscle magnetic resonance imaging, electromyography, creatine kinase blood level, IIM antibody panel and, as a final diagnostic step, muscle biopsy. Muscle biopsies were taken from affected muscles. In cases where no other muscles showed abnormalities, the cricopharyngeal muscle was targeted.
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Authors from the University of Münster
| Beule, Achim Georg | Clinic for Otorhinolaryngology, Head and Neck Surgery |
| Claus, Inga | Department for Neurology |
| Labeit, Bendix Ruven | Department for Neurology |
| Muhle, Paul | Department for Neurology |
| Roderigo, Malte Christian | Department for Neurology |
| Suntrup-Krüger, Sonja | Department for Neurology |
| Wiendl, Heinz Siegfried | Department for Neurology |