Detecting myasthenia gravis as a cause of unclear dysphagia with an endoscopic tensilon test.

Warnecke, Tobias; Im, Sun; Labeit, Bendix; Zwolinskaya, Olga, Suntrup-Krüger, Sonja; Oelenberg, Stephan; Ahring, Sigrid; Schilling, Matthias; Meuth, Sven; Melzer, Nico; Wiendl, Heinz; Ruck, Tobias; Dziewas, Rainer

Abstract

In this single-centre pragmatic clinical cohort study, a total of 100 patients with unclear pharyngeal dysphagia were eligible to undergo FTT. All patients were subjected to FTT and subsequently followed up clinically. FTT was considered positive if a significant improvement of pharyngeal swallowing function could be objectified endoscopically upon administration of edrophonium chloride. In addition, repetitive nerve stimulation test and serum MG antibody analysis were conducted.