Biophysical Analysis of Acute and Late Toxicity of Radiotherapy in Gastric Marginal Zone Lymphoma—Impact of Radiation Dose and Planning Target Volume

Reinartz Gabriele, Baehr Andrea, Kittel Christopher, Oertel Michael, Haverkamp Uwe, Eich Hans Theodor

Abstract

Prospective evaluation of impact of dose and target volume in radiation planning of gastric lymphoma on organs at risk. New model parameters for calculation of normal tissue complication probabilities were developed from quality-assured cohort data. The study provides practicable data to calculate risks for neighbored organs at risk in modern radiation planning with currently lower radiation doses, representing a basis for future adaptation of previous model parameters.