Non-canonical chemical feedback self-limits nitric oxide-cyclic GMP signaling in health and disease.
Dao, Vu Thao-Vi, Elbatreek, Mahmoud H, Deile, Martin, Nedvetsky, Pavel I, Güldner, Andreas, Ibarra-Alvarado, César, Gödecke, Axel, Schmidt, Harald H H W
Research article (journal) | Peer reviewed
Details about the publication
Journal: Scientific Reports (Sci. Rep.)
Volume: 10
Issue: Nitric oxide (NO)-cyclic GMP (cGMP) signaling is a vasoprotective pathway therapeutically targeted, for example, in pulmonary hypertension. Its dysregulation in disease is incompletely understood. Here we show in pulmonary artery endothelial cells that fee